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Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering

Surgical restoration of extensive tracheal lesions is complicated, and it necessitates the use of a biocompatible, mechanically stable, and non-toxic material that degrades gradually to overcome the limitation of allografts. A three-dimensional (3D) printed tracheal scaffold produced from polymers i...

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Main Author: Samat, Asmak Abdul
Format: Thesis
Language:English
Published: 2023
Subjects:
R5-920 Medicine (General)
Online Access:http://eprints.usm.my/61260/1/24%20Pages%20from%20ASMAK%20BINTI%20ABDUL%20SAMAT.pdf
http://eprints.usm.my/61260/
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spelling my.usm.eprints.61260 http://eprints.usm.my/61260/ Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering Samat, Asmak Abdul R5-920 Medicine (General) Surgical restoration of extensive tracheal lesions is complicated, and it necessitates the use of a biocompatible, mechanically stable, and non-toxic material that degrades gradually to overcome the limitation of allografts. A three-dimensional (3D) printed tracheal scaffold produced from polymers is one option for addressing some of the challenges in tracheal transplantation. Polymer blending is one approach for creating material with specific properties for a trachea scaffold. The goal of this study was to evaluate the physical, mechanical, and biological properties of thermoplastic polyurethane (TPU) and polylactic acid (PLA) blend as prospective tracheal replacement materials. Both materials are well-known for their promising properties when utilised independently, thus broadly employed in various applications, especially in the biomedical field. It is hypothesised that combining the two materials and the subsequent 3D printing method produces a composite with suitable qualities for tracheal replacement. Different TPU and PLA compositions were melt-blended and characterised for their physical and mechanical properties, 2023-02 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/61260/1/24%20Pages%20from%20ASMAK%20BINTI%20ABDUL%20SAMAT.pdf Samat, Asmak Abdul (2023) Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering. PhD thesis, Perpustakaan Hamzah Sendut.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Samat, Asmak Abdul
Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
description Surgical restoration of extensive tracheal lesions is complicated, and it necessitates the use of a biocompatible, mechanically stable, and non-toxic material that degrades gradually to overcome the limitation of allografts. A three-dimensional (3D) printed tracheal scaffold produced from polymers is one option for addressing some of the challenges in tracheal transplantation. Polymer blending is one approach for creating material with specific properties for a trachea scaffold. The goal of this study was to evaluate the physical, mechanical, and biological properties of thermoplastic polyurethane (TPU) and polylactic acid (PLA) blend as prospective tracheal replacement materials. Both materials are well-known for their promising properties when utilised independently, thus broadly employed in various applications, especially in the biomedical field. It is hypothesised that combining the two materials and the subsequent 3D printing method produces a composite with suitable qualities for tracheal replacement. Different TPU and PLA compositions were melt-blended and characterised for their physical and mechanical properties,
format Thesis
author Samat, Asmak Abdul
author_facet Samat, Asmak Abdul
author_sort Samat, Asmak Abdul
title Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_short Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_full Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_fullStr Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_full_unstemmed Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_sort physico-mechanical and biological evaluation of three-dimensional printed thermoplastic polyurethane and polylactic acid scaffold for tracheal tissue engineering
publishDate 2023
url http://eprints.usm.my/61260/1/24%20Pages%20from%20ASMAK%20BINTI%20ABDUL%20SAMAT.pdf
http://eprints.usm.my/61260/
_version_ 1814048428493111296
score 13.211869

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