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An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients

The recent availability of retinal imaging device plays an important role to differentiate the appearance of optic nerve in normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) patients. There no published literature of these two group of glaucoma in patients of Malay ethnicity, o...

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Main Author: Rahim, Adlina Abdul
Format: Thesis
Language:English
Published: 2012
Subjects:
R Medicine (General)
Online Access:http://eprints.usm.my/60946/1/DR%20ADLINA%20BINTI%20ABDUL%20RAHIM%20-%20%20e.pdf
http://eprints.usm.my/60946/
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spelling my.usm.eprints.60946 http://eprints.usm.my/60946/ An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients Rahim, Adlina Abdul R Medicine (General) The recent availability of retinal imaging device plays an important role to differentiate the appearance of optic nerve in normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) patients. There no published literature of these two group of glaucoma in patients of Malay ethnicity, or even those who are living in South East Asian areas. To compare optic nerve head parameters among Malay NTG and POAG patients using HR.T III analysis. A comparative cross sectional study was carried out from November 2010 till February 2012 in two hospitals with availability of glaucoma service. A total of 154 eyes of 154 Malay patients were included in this study; 32 NTG patients, 45 POAG patients and 77 control group. All participants underwent a thorough ocular examination including visual acuity, subjective refraction, anterior segment and fundus examinations, Humphrey visual field 24-2, intraocular pressure measurement, gonioscopy examination and fundus photography. An assessment of optic nerve head parameters was conducted using FIRT III by an identified masked investigator in each hospital. Comparison of these two glaucoma groups was further analyzed according to the appearance on cup disc ratio on clinical assessment and AGIS scoring system. Both glaucoma groups had notably larger discs, larger cupping, smaller retinal rims area and thinner nerve fiber layers when compared to the control group (p<0.05). NTG patients revealed larger disc and cup areas when compared to the POAG patients (the mean (SD) for disc area was 2.65 (0.41) mm2 NTG group, and 2.40 (0.36) mm2 in POAG group, p = 0.006; the mean cup area (SD) of NTG patients was 1.54 (0.43) mm2 and 1.32 (0.40) mm2 in POAG group, p = 0.027). This observation was also parallel when they were further analyzed according to the severity of glaucoma in both studied groups. The optic nerve head parameters are significantly different in Malay NTG and POAG patients when compared to healthy individuals. Disc and cup areas are significantly larger in Malay NTG compared to POAG patients, while the other parameters are comparable in both groups. 2012 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/60946/1/DR%20ADLINA%20BINTI%20ABDUL%20RAHIM%20-%20%20e.pdf Rahim, Adlina Abdul (2012) An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Rahim, Adlina Abdul
An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
description The recent availability of retinal imaging device plays an important role to differentiate the appearance of optic nerve in normal tension glaucoma (NTG) and primary open angle glaucoma (POAG) patients. There no published literature of these two group of glaucoma in patients of Malay ethnicity, or even those who are living in South East Asian areas. To compare optic nerve head parameters among Malay NTG and POAG patients using HR.T III analysis. A comparative cross sectional study was carried out from November 2010 till February 2012 in two hospitals with availability of glaucoma service. A total of 154 eyes of 154 Malay patients were included in this study; 32 NTG patients, 45 POAG patients and 77 control group. All participants underwent a thorough ocular examination including visual acuity, subjective refraction, anterior segment and fundus examinations, Humphrey visual field 24-2, intraocular pressure measurement, gonioscopy examination and fundus photography. An assessment of optic nerve head parameters was conducted using FIRT III by an identified masked investigator in each hospital. Comparison of these two glaucoma groups was further analyzed according to the appearance on cup disc ratio on clinical assessment and AGIS scoring system. Both glaucoma groups had notably larger discs, larger cupping, smaller retinal rims area and thinner nerve fiber layers when compared to the control group (p<0.05). NTG patients revealed larger disc and cup areas when compared to the POAG patients (the mean (SD) for disc area was 2.65 (0.41) mm2 NTG group, and 2.40 (0.36) mm2 in POAG group, p = 0.006; the mean cup area (SD) of NTG patients was 1.54 (0.43) mm2 and 1.32 (0.40) mm2 in POAG group, p = 0.027). This observation was also parallel when they were further analyzed according to the severity of glaucoma in both studied groups. The optic nerve head parameters are significantly different in Malay NTG and POAG patients when compared to healthy individuals. Disc and cup areas are significantly larger in Malay NTG compared to POAG patients, while the other parameters are comparable in both groups.
format Thesis
author Rahim, Adlina Abdul
author_facet Rahim, Adlina Abdul
author_sort Rahim, Adlina Abdul
title An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_short An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_full An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_fullStr An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_full_unstemmed An assessment of optic nerve parameters in Malay normal tension glaucoma and Primary open angle glaucoma patients
title_sort assessment of optic nerve parameters in malay normal tension glaucoma and primary open angle glaucoma patients
publishDate 2012
url http://eprints.usm.my/60946/1/DR%20ADLINA%20BINTI%20ABDUL%20RAHIM%20-%20%20e.pdf
http://eprints.usm.my/60946/
_version_ 1809137799224360960
score 13.211869

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