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Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control

Mosquito-borne diseases are increasing every year and causing million deaths worldwide. The diseases are transmitted from the bite of an infected mosquito. Thus, it requires effective control measures to reduce the transmission rate, and one of the control strategies is using larvicide such as te...

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Main Author: Pengiran, Hazirah
Format: Thesis
Language:English
Published: 2022
Subjects:
R5-920 Medicine (General)
Online Access:http://eprints.usm.my/59361/1/HAZIRAH%20BINTI%20PENGIRAN%20-%20TESIS24.pdf
http://eprints.usm.my/59361/
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spelling my.usm.eprints.59361 http://eprints.usm.my/59361/ Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control Pengiran, Hazirah R5-920 Medicine (General) Mosquito-borne diseases are increasing every year and causing million deaths worldwide. The diseases are transmitted from the bite of an infected mosquito. Thus, it requires effective control measures to reduce the transmission rate, and one of the control strategies is using larvicide such as temephos. Currently, the carrier materials used in the larvicide formulation raised environmental concerns due to their nonrenewable sources. The cellulose nanofiber from kenaf is seen as a sustainable replacement for larvicide carrier. The objectives of this study are to determine the capability of kenaf cellulose nanofiber (KCNF) to disperse and load temephos, the stability of KCNF impregnated with temephos (KCNF+T) in retaining temephos, the acute systemic toxicity of KCNF and KNCF+T in mammals, the acute ecotoxicity of KCNF in the aquatic organisms and the bioefficacy of KCNF+T as a larvicide carrier against Aedes aegypti mosquito larvae. The capability of KCNF to disperse is determined using the method adopted from OECD TG 318 and loading capability is evaluated using various water volume loaded on the dry KCNF. The amount of temephos impregnated on KCNF is quantified by HPLC analysis. KCNF is found to have high dispersion capability with more than 50 % dispersibility in six out of nine tested hydrochemical conditions and loading capability 6-fold of its mass. Amount of temephos impregnated on KCNF is found 1.94 % w/w reflecting 97 % impregnation efficacy. 2022-06 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/59361/1/HAZIRAH%20BINTI%20PENGIRAN%20-%20TESIS24.pdf Pengiran, Hazirah (2022) Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Pengiran, Hazirah
Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
description Mosquito-borne diseases are increasing every year and causing million deaths worldwide. The diseases are transmitted from the bite of an infected mosquito. Thus, it requires effective control measures to reduce the transmission rate, and one of the control strategies is using larvicide such as temephos. Currently, the carrier materials used in the larvicide formulation raised environmental concerns due to their nonrenewable sources. The cellulose nanofiber from kenaf is seen as a sustainable replacement for larvicide carrier. The objectives of this study are to determine the capability of kenaf cellulose nanofiber (KCNF) to disperse and load temephos, the stability of KCNF impregnated with temephos (KCNF+T) in retaining temephos, the acute systemic toxicity of KCNF and KNCF+T in mammals, the acute ecotoxicity of KCNF in the aquatic organisms and the bioefficacy of KCNF+T as a larvicide carrier against Aedes aegypti mosquito larvae. The capability of KCNF to disperse is determined using the method adopted from OECD TG 318 and loading capability is evaluated using various water volume loaded on the dry KCNF. The amount of temephos impregnated on KCNF is quantified by HPLC analysis. KCNF is found to have high dispersion capability with more than 50 % dispersibility in six out of nine tested hydrochemical conditions and loading capability 6-fold of its mass. Amount of temephos impregnated on KCNF is found 1.94 % w/w reflecting 97 % impregnation efficacy.
format Thesis
author Pengiran, Hazirah
author_facet Pengiran, Hazirah
author_sort Pengiran, Hazirah
title Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_short Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_full Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_fullStr Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_full_unstemmed Studies Of Capability, Stability, Toxicity And Bioefficacy Of Kenaf Based Cellulose Nanofiber As Larvicide Carrier For Mosquito Control
title_sort studies of capability, stability, toxicity and bioefficacy of kenaf based cellulose nanofiber as larvicide carrier for mosquito control
publishDate 2022
url http://eprints.usm.my/59361/1/HAZIRAH%20BINTI%20PENGIRAN%20-%20TESIS24.pdf
http://eprints.usm.my/59361/
_version_ 1778162349557940224
score 13.211869

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