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Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer

Objective: The aim of this work was to determine doses to rectum and bladder for dose behaviors in the treatment of cervical cancer by high dose rate (HDR) intracavitary brachytherapy (ICRT) using Ocentra treatment planning system. Materials and methods: A retrospective study was carried out on 1...

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Main Author: Azmi, Norazrien Suhaila Nor
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia 2015
Subjects:
R Medicine
RC254-282 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:http://eprints.usm.my/58000/1/NORAZRIEN%20SUHAILA%20BINTI%20NOR%20AZMI-24%20pages.pdf
http://eprints.usm.my/58000/
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spelling my.usm.eprints.58000 http://eprints.usm.my/58000/ Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer Azmi, Norazrien Suhaila Nor R Medicine RC254-282 Neoplasms. Tumors. Oncology (including Cancer) Objective: The aim of this work was to determine doses to rectum and bladder for dose behaviors in the treatment of cervical cancer by high dose rate (HDR) intracavitary brachytherapy (ICRT) using Ocentra treatment planning system. Materials and methods: A retrospective study was carried out on 1 0 patients with a total of 20 fractions (1 51 and 251 fractions for each patient) of cervical cancer treated with HDR intracavitary brachytherapy in addition to external radiotherapy (EBRT). Brachytherapy treatment planning was performed using Ocentra Treatment Planning System (Nucletron). Before this, the treatment was done using Plato treatment planning. Fletcher-suit applicators (Nucletron) with different size of ovoid which are mini (1.5 mm), small (2.0mm) and medium (2.5mm) are used for ICBT. The prescribed doses 900 cGy (9 Gy) for each fraction is normalised at applicator point. Normal distributions were tested for the rectum and bladder doses for any statistical conclusions. Results: It was observed that rICUR and bICRU were found to show normal distribution for fraction one with mean dose of 38% and 46% and standard deviation of 16% and 17%, respectively. Then rICUR and bICRU for fraction two with mean dose of 35% and 41% and standard deviation of 13% and 1 0 % respectively. Conclusions: The normality behavior of the rectal and bladder point dose show that less than 60% and 80 % of the prescribed dose at point A which means is in the limit of International Commission on Radiation Units (ICRU). Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia 2015-05 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/58000/1/NORAZRIEN%20SUHAILA%20BINTI%20NOR%20AZMI-24%20pages.pdf Azmi, Norazrien Suhaila Nor (2015) Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer. Project Report. Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia. (Submitted)
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R Medicine
RC254-282 Neoplasms. Tumors. Oncology (including Cancer)
spellingShingle R Medicine
RC254-282 Neoplasms. Tumors. Oncology (including Cancer)
Azmi, Norazrien Suhaila Nor
Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer
description Objective: The aim of this work was to determine doses to rectum and bladder for dose behaviors in the treatment of cervical cancer by high dose rate (HDR) intracavitary brachytherapy (ICRT) using Ocentra treatment planning system. Materials and methods: A retrospective study was carried out on 1 0 patients with a total of 20 fractions (1 51 and 251 fractions for each patient) of cervical cancer treated with HDR intracavitary brachytherapy in addition to external radiotherapy (EBRT). Brachytherapy treatment planning was performed using Ocentra Treatment Planning System (Nucletron). Before this, the treatment was done using Plato treatment planning. Fletcher-suit applicators (Nucletron) with different size of ovoid which are mini (1.5 mm), small (2.0mm) and medium (2.5mm) are used for ICBT. The prescribed doses 900 cGy (9 Gy) for each fraction is normalised at applicator point. Normal distributions were tested for the rectum and bladder doses for any statistical conclusions. Results: It was observed that rICUR and bICRU were found to show normal distribution for fraction one with mean dose of 38% and 46% and standard deviation of 16% and 17%, respectively. Then rICUR and bICRU for fraction two with mean dose of 35% and 41% and standard deviation of 13% and 1 0 % respectively. Conclusions: The normality behavior of the rectal and bladder point dose show that less than 60% and 80 % of the prescribed dose at point A which means is in the limit of International Commission on Radiation Units (ICRU).
format Monograph
author Azmi, Norazrien Suhaila Nor
author_facet Azmi, Norazrien Suhaila Nor
author_sort Azmi, Norazrien Suhaila Nor
title Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer
title_short Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer
title_full Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer
title_fullStr Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer
title_full_unstemmed Evaluate the doses to the Organs At Risk (OAR) calculated by using oncentra treatment planning system for cervical cancer
title_sort evaluate the doses to the organs at risk (oar) calculated by using oncentra treatment planning system for cervical cancer
publisher Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia
publishDate 2015
url http://eprints.usm.my/58000/1/NORAZRIEN%20SUHAILA%20BINTI%20NOR%20AZMI-24%20pages.pdf
http://eprints.usm.my/58000/
_version_ 1765297641728507904
score 13.211869

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