Expression Level of Pro-Apoptotic Genes Determine Disease Severity of HbE/Beta thalassemia
• Hb E/(3-thalassemia is inherited disorders that occur as a result of abnormal synthesis of (3-globin • Co-inheritance of a-globin hemoglobinopathies and increase level of HbF have shown to modulate the presentation of Hb E/~-thalassemia J but not in all patients~ suggesting that other factors...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pusat Pengajian Sains Kesihatan, Universiti Sains Malaysia
2019
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/56991/1/DR%20ROSLINE%20HASSAN-Eprints.pdf http://eprints.usm.my/56991/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | • Hb E/(3-thalassemia is inherited disorders that occur as a result of
abnormal synthesis of (3-globin
• Co-inheritance of a-globin hemoglobinopathies and increase level of
HbF have shown to modulate the presentation of Hb E/~-thalassemia J
but not in all patients~ suggesting that other factors may contribute to
heterogeneity of the disease.
• Hb E/~-thalassemia presented with a wide range of disease severity1
ranging from essentially asymptomatic to a severe transfusiondependent state |
|---|