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Valuation Of Eq-5d-5l Study For The Malaysian Population

With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes i...

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Main Author: Thakumar, Annushiah Vasan
Format: Thesis
Language:English
Published: 2020
Subjects:
RS1-441 Pharmacy and materia medica
Online Access:http://eprints.usm.my/54974/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf
http://eprints.usm.my/54974/
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spelling my.usm.eprints.54974 http://eprints.usm.my/54974/ Valuation Of Eq-5d-5l Study For The Malaysian Population Thakumar, Annushiah Vasan RS1-441 Pharmacy and materia medica With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes into consideration health preference weights, with generic preference-based measures (PBMs) being most commonly used to generate these weights. One of the most widely used instrument todate, EQ-5D-5L has informed economic evaluation decisions throughout the world. However, Malaysia has yet to validate the measure and apply it to generate a countryspecific value set. Therefore, the main objective of this thesis is to estimate a valid EQ- 5D-5L value set for Malaysians. Two focus group discussions (FGDs) were held to explore the EQ-5D-5L dimensions understanding in Malaysians and investigate potential dimensions (bolt-ons) that may complement the concept of health. Next, using 100 conveniently sampled respondents, the influence of these identified bolt-ons on the current EQ-5D-5L dimensions were tested in a pilot setting in Penang. Subsequently, employing a cross-sectional multi-stage sampling design, an EQ-5D-5L nationwide valuation study was carried out by 18 trained interviewers on 1137 Malaysian general population. The psychometric properties of EQ-5D-5L were also assessed in the process. A variety of modelling methods were fitted onto the valuation data and performance of these models in predicting health state values were assessed using robust techniques. 2020-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/54974/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf Thakumar, Annushiah Vasan (2020) Valuation Of Eq-5d-5l Study For The Malaysian Population. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Thakumar, Annushiah Vasan
Valuation Of Eq-5d-5l Study For The Malaysian Population
description With the rise of healthcare expenditure, prudent resource allocation decisions become vital and economic evaluations offer valuable information in guiding these decisions. Cost-utility analysis is one such alternative with outcomes measured using quality-adjusted life years (QALYs). QALYs takes into consideration health preference weights, with generic preference-based measures (PBMs) being most commonly used to generate these weights. One of the most widely used instrument todate, EQ-5D-5L has informed economic evaluation decisions throughout the world. However, Malaysia has yet to validate the measure and apply it to generate a countryspecific value set. Therefore, the main objective of this thesis is to estimate a valid EQ- 5D-5L value set for Malaysians. Two focus group discussions (FGDs) were held to explore the EQ-5D-5L dimensions understanding in Malaysians and investigate potential dimensions (bolt-ons) that may complement the concept of health. Next, using 100 conveniently sampled respondents, the influence of these identified bolt-ons on the current EQ-5D-5L dimensions were tested in a pilot setting in Penang. Subsequently, employing a cross-sectional multi-stage sampling design, an EQ-5D-5L nationwide valuation study was carried out by 18 trained interviewers on 1137 Malaysian general population. The psychometric properties of EQ-5D-5L were also assessed in the process. A variety of modelling methods were fitted onto the valuation data and performance of these models in predicting health state values were assessed using robust techniques.
format Thesis
author Thakumar, Annushiah Vasan
author_facet Thakumar, Annushiah Vasan
author_sort Thakumar, Annushiah Vasan
title Valuation Of Eq-5d-5l Study For The Malaysian Population
title_short Valuation Of Eq-5d-5l Study For The Malaysian Population
title_full Valuation Of Eq-5d-5l Study For The Malaysian Population
title_fullStr Valuation Of Eq-5d-5l Study For The Malaysian Population
title_full_unstemmed Valuation Of Eq-5d-5l Study For The Malaysian Population
title_sort valuation of eq-5d-5l study for the malaysian population
publishDate 2020
url http://eprints.usm.my/54974/1/ANNUSHIAH%20AP%20VASAN%20THAKUMAR%20-%20TESIS%20cut.pdf
http://eprints.usm.my/54974/
_version_ 1745563215334473728
score 13.211869

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