57th. Annual National Conference of Indian Society of Anaestbesiologists 2009 Chennai, India 26 - 30 Dis ember 2009
Background end goals of study. to evaluate the eflicacy,safety,tolerability & side effect between of pregabalin, gabapentin and topiramate in chronic pain management Methods: Prospective, double blind,randomized controlled trial of 12 weeks duration comparing pregabalin, gabapentin & topi...
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Pusat Pengajian Sains Perubatan
2009
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my.usm.eprints.54580 http://eprints.usm.my/54580/ 57th. Annual National Conference of Indian Society of Anaestbesiologists 2009 Chennai, India 26 - 30 Dis ember 2009 Gnandev, Pbutane R Medicine (General) Background end goals of study. to evaluate the eflicacy,safety,tolerability & side effect between of pregabalin, gabapentin and topiramate in chronic pain management Methods: Prospective, double blind,randomized controlled trial of 12 weeks duration comparing pregabalin, gabapentin & topiramate. Study was conducted on patient with chronic pain clinic at LLRH, Kanpur. Participants were 120 patients with chronic pain. Tha primary outcome was difference between pregabalin, gabapentine & topiramate in chronic pain, as measured by the mean VAS score computed over weekly of each treatment period.Secondary outcomes were changes in mood, quality of life & psychomotor functions.Side effects were measured by questionnaire. Patient received a maximum dally dose of 600 mg gabapentine or 400 mg pregabalin or 1 00 mg topiramate along with 300 mg aceclofenac Results: Mean baselineVAS was 69.6 mm (29.4-95.2) on a scale of 0-100mm.120 patients were included in the available case analysis & 30 patients in the per protocol analysis. The mean score was 6mm longer for gabapentine than for pregabalin & topiramate in the available case analysis & 5.6 mm in the per protocol analysis. Cone/us/on: Gabapentine provided better pain relief than the pregabalin & topiramate & had slightly fewer side effects, well tolerable, although no major adverse events occur for either drug. Pusat Pengajian Sains Perubatan 2009 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/54580/1/DR%20GNANDEV%20PHUTANE%20-%20e.pdf Gnandev, Pbutane (2009) 57th. Annual National Conference of Indian Society of Anaestbesiologists 2009 Chennai, India 26 - 30 Dis ember 2009. Other. Pusat Pengajian Sains Perubatan. (Submitted) |
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R Medicine (General) Gnandev, Pbutane 57th. Annual National Conference of Indian Society of Anaestbesiologists 2009 Chennai, India 26 - 30 Dis ember 2009 |
| description |
Background end goals of study. to evaluate the eflicacy,safety,tolerability & side effect between
of pregabalin, gabapentin and topiramate in chronic pain management
Methods: Prospective, double blind,randomized controlled trial of 12 weeks duration comparing
pregabalin, gabapentin & topiramate. Study was conducted on patient with chronic pain clinic at
LLRH, Kanpur. Participants were 120 patients with chronic pain. Tha primary outcome was
difference between pregabalin, gabapentine & topiramate in chronic pain, as measured by the
mean VAS score computed over weekly of each treatment period.Secondary outcomes were
changes in mood, quality of life & psychomotor functions.Side effects were measured by
questionnaire. Patient received a maximum dally dose of 600 mg gabapentine or 400 mg
pregabalin or 1 00 mg topiramate along with 300 mg aceclofenac
Results: Mean baselineVAS was 69.6 mm (29.4-95.2) on a scale of 0-100mm.120 patients were
included in the available case analysis & 30 patients in the per protocol analysis. The mean score
was 6mm longer for gabapentine than for pregabalin & topiramate in the available case analysis &
5.6 mm in the per protocol analysis.
Cone/us/on: Gabapentine provided better pain relief than the pregabalin & topiramate & had
slightly fewer side effects, well tolerable, although no major adverse events occur for either drug. |
| format |
Monograph |
| author |
Gnandev, Pbutane |
| author_facet |
Gnandev, Pbutane |
| author_sort |
Gnandev, Pbutane |
| title |
57th. Annual National Conference of Indian Society of
Anaestbesiologists 2009
Chennai, India
26 - 30 Dis ember 2009 |
| title_short |
57th. Annual National Conference of Indian Society of
Anaestbesiologists 2009
Chennai, India
26 - 30 Dis ember 2009 |
| title_full |
57th. Annual National Conference of Indian Society of
Anaestbesiologists 2009
Chennai, India
26 - 30 Dis ember 2009 |
| title_fullStr |
57th. Annual National Conference of Indian Society of
Anaestbesiologists 2009
Chennai, India
26 - 30 Dis ember 2009 |
| title_full_unstemmed |
57th. Annual National Conference of Indian Society of
Anaestbesiologists 2009
Chennai, India
26 - 30 Dis ember 2009 |
| title_sort |
57th. annual national conference of indian society of
anaestbesiologists 2009
chennai, india
26 - 30 dis ember 2009 |
| publisher |
Pusat Pengajian Sains Perubatan |
| publishDate |
2009 |
| url |
http://eprints.usm.my/54580/1/DR%20GNANDEV%20PHUTANE%20-%20e.pdf http://eprints.usm.my/54580/ |
| _version_ |
1744354443420237824 |
| score |
13.211869 |