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Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application

Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct metho...

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Main Author: Dheyab, Mohammed Ali
Format: Thesis
Language:English
Published: 2021
Subjects:
QC1 Physics (General)
Online Access:http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf
http://eprints.usm.my/52055/
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spelling my.usm.eprints.52055 http://eprints.usm.my/52055/ Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application Dheyab, Mohammed Ali QC1 Physics (General) Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct methods for Fe3O4@Au NPs synthesis are laborious and time-consuming. Therefore, this study presents a facile and rapid sonochemical technique of synthesising Fe3O4@Au NPs with excellent physicochemical properties for magnetic resonance imaging (MRI) and computed tomography (CT) scan. The Au shell is coated on Fe3O4 NPs using a Vibra-Cell ultrasonic solid horn with tip size, frequency and power output of ½ inch, 20 kHz and 750 watts, respectively within 10 minutes. The targeted zeta potential of - 46.125 mV was achieved under the optimum conditions of 10 ml of HAuCl4, 30 ml of sodium citrate (SC) and sonication amplitude of 40%, which is consistent (about 99.2%) with the actual average zeta potential (- 45.8 mV). The stability and monodispersing of Fe3O4NPs improved following modification to Fe3O4@Au, as indicated by the increase in zeta potential from - 24.2 mV to - 45.8 mV. The saturation magnetization (Ms) value of Fe3O4 was 54 emu/g, while that of Fe3O4@Au NP is 38 emu/g. In general, the sonochemical method effectively synthesis highly stable and monodisperse Fe3O4@Au NPs with an average size of about 20 nm within 10 minutes. 2021-02 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf Dheyab, Mohammed Ali (2021) Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application. PhD thesis, Perpustakaan Hamzah Sendut.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic QC1 Physics (General)
spellingShingle QC1 Physics (General)
Dheyab, Mohammed Ali
Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
description Core@shell nanoparticles (Fe3O4@Au NPs) have multiple functions obtained in one stable entity and thus have been extensively investigated. Combining Fe3O4 and Au NPs in one core@shell nanostructure is a promising strategy for diagnostic biomedical applications. However, the conventional direct methods for Fe3O4@Au NPs synthesis are laborious and time-consuming. Therefore, this study presents a facile and rapid sonochemical technique of synthesising Fe3O4@Au NPs with excellent physicochemical properties for magnetic resonance imaging (MRI) and computed tomography (CT) scan. The Au shell is coated on Fe3O4 NPs using a Vibra-Cell ultrasonic solid horn with tip size, frequency and power output of ½ inch, 20 kHz and 750 watts, respectively within 10 minutes. The targeted zeta potential of - 46.125 mV was achieved under the optimum conditions of 10 ml of HAuCl4, 30 ml of sodium citrate (SC) and sonication amplitude of 40%, which is consistent (about 99.2%) with the actual average zeta potential (- 45.8 mV). The stability and monodispersing of Fe3O4NPs improved following modification to Fe3O4@Au, as indicated by the increase in zeta potential from - 24.2 mV to - 45.8 mV. The saturation magnetization (Ms) value of Fe3O4 was 54 emu/g, while that of Fe3O4@Au NP is 38 emu/g. In general, the sonochemical method effectively synthesis highly stable and monodisperse Fe3O4@Au NPs with an average size of about 20 nm within 10 minutes.
format Thesis
author Dheyab, Mohammed Ali
author_facet Dheyab, Mohammed Ali
author_sort Dheyab, Mohammed Ali
title Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
title_short Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
title_full Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
title_fullStr Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
title_full_unstemmed Iron Oxide Encapsulated Gold Colloidal Nanoparticle Via Rapid Sonochemical Method For Mri And Ct Imaging Application
title_sort iron oxide encapsulated gold colloidal nanoparticle via rapid sonochemical method for mri and ct imaging application
publishDate 2021
url http://eprints.usm.my/52055/1/MOHAMMED%20ALI%20DHEYAB.pdf
http://eprints.usm.my/52055/
_version_ 1729703910349733888
score 13.211869

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