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Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines

Quercus infectoria is an oak tree available in Asia Minor include Greece and Iran. The project is conducted to evaluate the antiproliferative activity of Quercus infectoria Olivier galls' extracts in vitro. Three extracts from aqueous crude extract by soaking and soxhlet method, one extract...

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Main Author: Chow Cheah, Yen
Format: Monograph
Language:English
Published: Universiti Sains Malaysia 2009
Subjects:
R Medicine (General)
Online Access:http://eprints.usm.my/51034/1/CHOW%20CHEAH%20YEN%20-%2024%20pages.pdf
http://eprints.usm.my/51034/
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spelling my.usm.eprints.51034 http://eprints.usm.my/51034/ Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines Chow Cheah, Yen R Medicine (General) Quercus infectoria is an oak tree available in Asia Minor include Greece and Iran. The project is conducted to evaluate the antiproliferative activity of Quercus infectoria Olivier galls' extracts in vitro. Three extracts from aqueous crude extract by soaking and soxhlet method, one extract from ethanol crude extract by soaking method and one extract from methanol extract by soaking method were used. All the five crude extracts were used to treat HeLa and Caov-3 cancer cells line to screen for their antiproliferative activity. All the extracts shown to have ICso less than 100 Jlg/ml. Among them, the highest antiproliferative activity ofiC50 2.82 Jlg/ml was shown by the ethanol crude extract treated HeLa cancer cell lines. HeLa cells (most potent cell lines) was then treaed with ethanol crude extract for 24,48 and 72 hours and stain with dye Hoescht stain 33258 stain to demonstrate the morphological changes occur in cell and nuclear membrane as a result of apoptosis. In conclusion, Quercus infectoria galls' extracts contain potentially active compounds that act as anticancer agent. Universiti Sains Malaysia 2009 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/51034/1/CHOW%20CHEAH%20YEN%20-%2024%20pages.pdf Chow Cheah, Yen (2009) Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines. Other. Universiti Sains Malaysia. (Submitted)
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Chow Cheah, Yen
Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines
description Quercus infectoria is an oak tree available in Asia Minor include Greece and Iran. The project is conducted to evaluate the antiproliferative activity of Quercus infectoria Olivier galls' extracts in vitro. Three extracts from aqueous crude extract by soaking and soxhlet method, one extract from ethanol crude extract by soaking method and one extract from methanol extract by soaking method were used. All the five crude extracts were used to treat HeLa and Caov-3 cancer cells line to screen for their antiproliferative activity. All the extracts shown to have ICso less than 100 Jlg/ml. Among them, the highest antiproliferative activity ofiC50 2.82 Jlg/ml was shown by the ethanol crude extract treated HeLa cancer cell lines. HeLa cells (most potent cell lines) was then treaed with ethanol crude extract for 24,48 and 72 hours and stain with dye Hoescht stain 33258 stain to demonstrate the morphological changes occur in cell and nuclear membrane as a result of apoptosis. In conclusion, Quercus infectoria galls' extracts contain potentially active compounds that act as anticancer agent.
format Monograph
author Chow Cheah, Yen
author_facet Chow Cheah, Yen
author_sort Chow Cheah, Yen
title Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines
title_short Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines
title_full Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines
title_fullStr Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines
title_full_unstemmed Antiproliferative activity of quercus infector/A galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines
title_sort antiproliferative activity of quercus infector/a galls extracts towards helaand caov-3 cancer cells and its apoptosis inducing activity on selected cancer cell lines
publisher Universiti Sains Malaysia
publishDate 2009
url http://eprints.usm.my/51034/1/CHOW%20CHEAH%20YEN%20-%2024%20pages.pdf
http://eprints.usm.my/51034/
_version_ 1724074403663183872
score 13.211869

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