Cover Image

The antimicrobial potential effects of malaysian honey on some human pathogens

Honey is a nutrient food nutrient. It was also reported to have potential antimicrobial effects and medication values since centuries ago. Malaysian honeys are well recognized because of their quality. Thus, in this study Malaysian honey (Madu Liar™) was tested against several strains of human pa...

Full description

Saved in:
Bibliographic Details
Main Author: Ng Wen, Jie
Format: Monograph
Language:English
Published: Pusat Pengajian Sains Perubatan Universiti Sains Malaysia 2008
Subjects:
R Medicine (General)
Online Access:http://eprints.usm.my/50698/1/NG%20WEN%20JIE%20-%2024%20pages.pdf
http://eprints.usm.my/50698/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.usm.eprints.50698
record_format eprints
spelling my.usm.eprints.50698 http://eprints.usm.my/50698/ The antimicrobial potential effects of malaysian honey on some human pathogens Ng Wen, Jie R Medicine (General) Honey is a nutrient food nutrient. It was also reported to have potential antimicrobial effects and medication values since centuries ago. Malaysian honeys are well recognized because of their quality. Thus, in this study Malaysian honey (Madu Liar™) was tested against several strains of human pathogens including gram positives, gram negatives, antibiotic-resistant bacteria and fungi. Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), Streptococcus bovis, Streptococcus pyogenes Group A, Listeria monocytogenes, Enterococcus faecalis, Acinobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, Shigella sonnei, Klebsiella pneumoniae and Candida albicans were tested against different concentrations of honey broth media(%, v/v): 0%, I 0%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90% and I 00%. Duplicate were performed for each pathogen. The results showed S. pyogenes was the most sensitive in which totally inhibited in 30% concentration of honey broth media and followed by S. bovis, 40%; P. aeruginosa and A. baumannii, 50%; E. coli, K. pneumoniae and S. sonnei, 60%; L. monocytogenes and yeast C. albicans, 70% and the most resistant are E. faecalis, S. aurues and MRSA, 80%. LD50 (dose of the test chemical that is lethal to 50% of the bioassay organisms) for each pathogen was determined from each dose-response graph. S. bovisand P. aeruginosa have the lowest LD50, 4%, and followed by S. pyogenes, L. monocytogenes, A. baumannii and K. pneumoniae, 5%; S. aureus and E. coli, 9%; E.faecalis, 14%; MRSA, I5% and C. albicans has the highest LDso, 29%. This study showed that Malaysia's honey (Madu Liar™) prevented growth of a wide range of potential human pathogens in growth cultures and thus revealed its broad-spectrum antimicrobial activity. Pusat Pengajian Sains Perubatan Universiti Sains Malaysia 2008 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/50698/1/NG%20WEN%20JIE%20-%2024%20pages.pdf Ng Wen, Jie (2008) The antimicrobial potential effects of malaysian honey on some human pathogens. Other. Pusat Pengajian Sains Perubatan Universiti Sains Malaysia. (Submitted)
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Ng Wen, Jie
The antimicrobial potential effects of malaysian honey on some human pathogens
description Honey is a nutrient food nutrient. It was also reported to have potential antimicrobial effects and medication values since centuries ago. Malaysian honeys are well recognized because of their quality. Thus, in this study Malaysian honey (Madu Liar™) was tested against several strains of human pathogens including gram positives, gram negatives, antibiotic-resistant bacteria and fungi. Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), Streptococcus bovis, Streptococcus pyogenes Group A, Listeria monocytogenes, Enterococcus faecalis, Acinobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, Shigella sonnei, Klebsiella pneumoniae and Candida albicans were tested against different concentrations of honey broth media(%, v/v): 0%, I 0%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90% and I 00%. Duplicate were performed for each pathogen. The results showed S. pyogenes was the most sensitive in which totally inhibited in 30% concentration of honey broth media and followed by S. bovis, 40%; P. aeruginosa and A. baumannii, 50%; E. coli, K. pneumoniae and S. sonnei, 60%; L. monocytogenes and yeast C. albicans, 70% and the most resistant are E. faecalis, S. aurues and MRSA, 80%. LD50 (dose of the test chemical that is lethal to 50% of the bioassay organisms) for each pathogen was determined from each dose-response graph. S. bovisand P. aeruginosa have the lowest LD50, 4%, and followed by S. pyogenes, L. monocytogenes, A. baumannii and K. pneumoniae, 5%; S. aureus and E. coli, 9%; E.faecalis, 14%; MRSA, I5% and C. albicans has the highest LDso, 29%. This study showed that Malaysia's honey (Madu Liar™) prevented growth of a wide range of potential human pathogens in growth cultures and thus revealed its broad-spectrum antimicrobial activity.
format Monograph
author Ng Wen, Jie
author_facet Ng Wen, Jie
author_sort Ng Wen, Jie
title The antimicrobial potential effects of malaysian honey on some human pathogens
title_short The antimicrobial potential effects of malaysian honey on some human pathogens
title_full The antimicrobial potential effects of malaysian honey on some human pathogens
title_fullStr The antimicrobial potential effects of malaysian honey on some human pathogens
title_full_unstemmed The antimicrobial potential effects of malaysian honey on some human pathogens
title_sort antimicrobial potential effects of malaysian honey on some human pathogens
publisher Pusat Pengajian Sains Perubatan Universiti Sains Malaysia
publishDate 2008
url http://eprints.usm.my/50698/1/NG%20WEN%20JIE%20-%2024%20pages.pdf
http://eprints.usm.my/50698/
_version_ 1717094542061076480
score 13.211869

Similar Items