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A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia

Background: Hospital Universiti Sains Malaysia is the only centre in East Coast of Malaysia who offered bariatrics surgery services since October 2016. Bariatric surgery confers benefits to obese in terms of weight, blood pressure reduction and normalisation of blood sugars. However, the information...

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Main Author: Abidin, Muhd Abdul Ghani Zenol
Format: Thesis
Language:English
Published: 2020
Subjects:
RD Surgery
Online Access:http://eprints.usm.my/50297/1/MUHD%20ABDUL%20GHANI%20BIN%20ZENOL%20ABIDIN-24%20pages.pdf
http://eprints.usm.my/50297/
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spelling my.usm.eprints.50297 http://eprints.usm.my/50297/ A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia Abidin, Muhd Abdul Ghani Zenol RD Surgery Background: Hospital Universiti Sains Malaysia is the only centre in East Coast of Malaysia who offered bariatrics surgery services since October 2016. Bariatric surgery confers benefits to obese in terms of weight, blood pressure reduction and normalisation of blood sugars. However, the information on the effect of bariatric surgery in this centre is lacking. Methods: This retrospective study involving review of medical records of all patients underwent sleeve gastrectomy or Roux-en-Y gastric bypass in Hospital Universiti Sains Malaysia between October 2016 until July 2019. We analyse weight, blood pressure and biochemical parameters at baseline and 6 months post-surgery using student paired t-test. McNemar test is used to determine change in oral hypoglycaemic agents and/or total insulin dose, total number of anti-hypertensives and total number of anti-lipids. Result: A total of 39 patients were analysed. Mean weight reduction was 29.14 (95% CI = 24.75, 33.53) kg, SBP mean reduction was 17.87 (95% CI = 11.17, 24.58) mmHg and DBP mean reduction was 7.18 (95% CI = 3.21, 11.15) mmHg. Mean HbA1c reduction was 3.13 (95% CI = 2.07, 4.19) %, triglycerides mean reduction of 0.29 (95% CI = 0.12, 0.47) mmol/L. At 6 months post-surgery, 16 participants (61%) had remission in hypertension, 41% had reduction in number of antihypertensive. Eight patients (40%) had remission of diabetes and 4 patients (20%) who were diabetics becoming pre-diabetes. Only 4 patients were on oral hypoglycaemic agents and/or 3 patients were able to off insulin. Total insulin dose were markedly reduced, with median dose of 148 (34) iu to 24 (34) post-operatively. Five patients (25%) had normalisation of lipid profile and were able to off anti-lipids. Conclusion: Bariatric surgery among our patients with obesity confers significant metabolic benefits which is comparable to other centres. 2020 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/50297/1/MUHD%20ABDUL%20GHANI%20BIN%20ZENOL%20ABIDIN-24%20pages.pdf Abidin, Muhd Abdul Ghani Zenol (2020) A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RD Surgery
spellingShingle RD Surgery
Abidin, Muhd Abdul Ghani Zenol
A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
description Background: Hospital Universiti Sains Malaysia is the only centre in East Coast of Malaysia who offered bariatrics surgery services since October 2016. Bariatric surgery confers benefits to obese in terms of weight, blood pressure reduction and normalisation of blood sugars. However, the information on the effect of bariatric surgery in this centre is lacking. Methods: This retrospective study involving review of medical records of all patients underwent sleeve gastrectomy or Roux-en-Y gastric bypass in Hospital Universiti Sains Malaysia between October 2016 until July 2019. We analyse weight, blood pressure and biochemical parameters at baseline and 6 months post-surgery using student paired t-test. McNemar test is used to determine change in oral hypoglycaemic agents and/or total insulin dose, total number of anti-hypertensives and total number of anti-lipids. Result: A total of 39 patients were analysed. Mean weight reduction was 29.14 (95% CI = 24.75, 33.53) kg, SBP mean reduction was 17.87 (95% CI = 11.17, 24.58) mmHg and DBP mean reduction was 7.18 (95% CI = 3.21, 11.15) mmHg. Mean HbA1c reduction was 3.13 (95% CI = 2.07, 4.19) %, triglycerides mean reduction of 0.29 (95% CI = 0.12, 0.47) mmol/L. At 6 months post-surgery, 16 participants (61%) had remission in hypertension, 41% had reduction in number of antihypertensive. Eight patients (40%) had remission of diabetes and 4 patients (20%) who were diabetics becoming pre-diabetes. Only 4 patients were on oral hypoglycaemic agents and/or 3 patients were able to off insulin. Total insulin dose were markedly reduced, with median dose of 148 (34) iu to 24 (34) post-operatively. Five patients (25%) had normalisation of lipid profile and were able to off anti-lipids. Conclusion: Bariatric surgery among our patients with obesity confers significant metabolic benefits which is comparable to other centres.
format Thesis
author Abidin, Muhd Abdul Ghani Zenol
author_facet Abidin, Muhd Abdul Ghani Zenol
author_sort Abidin, Muhd Abdul Ghani Zenol
title A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_short A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_full A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_fullStr A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_full_unstemmed A study on the metabolic outcome of patients who underwent bariatric surgery in Hospital Universiti Sains Malaysia
title_sort study on the metabolic outcome of patients who underwent bariatric surgery in hospital universiti sains malaysia
publishDate 2020
url http://eprints.usm.my/50297/1/MUHD%20ABDUL%20GHANI%20BIN%20ZENOL%20ABIDIN-24%20pages.pdf
http://eprints.usm.my/50297/
_version_ 1715190769740939264
score 13.211869

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