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Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart)

Image-guided adaptive radiotherapy (IGART) is an advanced radiotherapy treatment technique that involves treatment plan modifications during the treatment course to account for temporal changes in tumour volume. The purpose of this study is to develop a Quality Assurance Programme (QAP) for a linac...

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Main Author: Sakaria, Kasmayanti
Format: Thesis
Language:English
Published: 2019
Subjects:
RK1-715 Dentistry
Online Access:http://eprints.usm.my/48594/1/MScThesis_KasmayantiSakaria_March2019%2024.pdf
http://eprints.usm.my/48594/
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spelling my.usm.eprints.48594 http://eprints.usm.my/48594/ Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart) Sakaria, Kasmayanti RK1-715 Dentistry Image-guided adaptive radiotherapy (IGART) is an advanced radiotherapy treatment technique that involves treatment plan modifications during the treatment course to account for temporal changes in tumour volume. The purpose of this study is to develop a Quality Assurance Programme (QAP) for a linac that is optimised for IGART. The linac investigated in this study is an Elekta Synergy linac with 80 pairs of multileaf collimators (MLC) and cone beam computed tomography (CBCT) image guidance system. An optimised QAP was developed to assess relevant linac performance parameters including dose output delivery, dynamic MLC and CBCT image guidance system. Linac dose output was measured daily using a cross-calibrated detector, Quickcheck. The parameters evaluated were central dose output, beam flatness, beam symmetry and beam quality for a period of 19 months. The variations of measurement were within the tolerance level. The central dose outputs are within ± 2%, the beam flatness results are within ± 1.5%, the beam symmetry results are within ± 3% and the beam quality results are within ± 3%. The dynamic MLC performance was analysed weekly in term of leaf positional accuracy using Elekta’s propriety MLC tracking system that is verified against EPID measurement. The MLC position errors tracked were between -0.30 mm to 0.80 mm, within the range of the results from EPID. The performance of CBCT image guidance system was assessed monthly in term of image quality and CT number accuracy using smaller sized CIRS 062QA and compared against the more commonly used Catphan 600. The interphantom variations were observed in the measured parameters, yet they have similar trend to each other. 2019-03 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/48594/1/MScThesis_KasmayantiSakaria_March2019%2024.pdf Sakaria, Kasmayanti (2019) Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart). Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RK1-715 Dentistry
spellingShingle RK1-715 Dentistry
Sakaria, Kasmayanti
Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart)
description Image-guided adaptive radiotherapy (IGART) is an advanced radiotherapy treatment technique that involves treatment plan modifications during the treatment course to account for temporal changes in tumour volume. The purpose of this study is to develop a Quality Assurance Programme (QAP) for a linac that is optimised for IGART. The linac investigated in this study is an Elekta Synergy linac with 80 pairs of multileaf collimators (MLC) and cone beam computed tomography (CBCT) image guidance system. An optimised QAP was developed to assess relevant linac performance parameters including dose output delivery, dynamic MLC and CBCT image guidance system. Linac dose output was measured daily using a cross-calibrated detector, Quickcheck. The parameters evaluated were central dose output, beam flatness, beam symmetry and beam quality for a period of 19 months. The variations of measurement were within the tolerance level. The central dose outputs are within ± 2%, the beam flatness results are within ± 1.5%, the beam symmetry results are within ± 3% and the beam quality results are within ± 3%. The dynamic MLC performance was analysed weekly in term of leaf positional accuracy using Elekta’s propriety MLC tracking system that is verified against EPID measurement. The MLC position errors tracked were between -0.30 mm to 0.80 mm, within the range of the results from EPID. The performance of CBCT image guidance system was assessed monthly in term of image quality and CT number accuracy using smaller sized CIRS 062QA and compared against the more commonly used Catphan 600. The interphantom variations were observed in the measured parameters, yet they have similar trend to each other.
format Thesis
author Sakaria, Kasmayanti
author_facet Sakaria, Kasmayanti
author_sort Sakaria, Kasmayanti
title Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart)
title_short Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart)
title_full Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart)
title_fullStr Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart)
title_full_unstemmed Optimisation Of Quality Assurance Programme (Qap) For Image-Guided Adaptive Radiotherapy (Igart)
title_sort optimisation of quality assurance programme (qap) for image-guided adaptive radiotherapy (igart)
publishDate 2019
url http://eprints.usm.my/48594/1/MScThesis_KasmayantiSakaria_March2019%2024.pdf
http://eprints.usm.my/48594/
_version_ 1695531541339308032
score 13.211869

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