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Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain

Introduction: To assess the effectiveness of nebulized fentanyl citrate in treating children presenting with acute severe pain of various aetiologies. Methods: Patients aged 5 to 15 years old presented with acute severe pain of any causes were enrolled into the study through convenient sampling a...

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Main Author: Yahaya, Raden Nezarul Raden
Format: Thesis
Language:English
Published: 2018
Subjects:
RD Surgery
Online Access:http://eprints.usm.my/47846/1/Dr.%20Raden%20Nazerul%20Raden%20Yahaya-24%20pages.pdf
http://eprints.usm.my/47846/
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spelling my.usm.eprints.47846 http://eprints.usm.my/47846/ Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain Yahaya, Raden Nezarul Raden RD Surgery Introduction: To assess the effectiveness of nebulized fentanyl citrate in treating children presenting with acute severe pain of various aetiologies. Methods: Patients aged 5 to 15 years old presented with acute severe pain of any causes were enrolled into the study through convenient sampling and received intravenous preparation of fentanyl citrate at dose of 4 mcg/kg administered through oxygen driven nebulizer circuit. Pain scores were assessed at pre-treatment and subsequently at 5 minutes interval until 60 minutes post-treatment using Wong and Baker faces pain scale. Vital signs and potential adverse events were also monitored. Results: 42 children with acute pain of various causes participated in this study and tolerated the nebulized fentanyl citrate well. 2 patients were withdrawn due to insufficient pain control post treatment. The pain aetiologies were categorized into fractures (n=14), soft tissue injuries (n=15) and abdominal pain (n=11). The mean pain score at 10 minutes on nebulized fentanyl administration decreased by 2.65 (95% CI 2.62 to 2.73) from the baseline. Pain score continued to decrease at 15 minutes (mean pain score difference 4.20; 95% CI 4.01 to 4.39) followed by a sustained plateau pain score at 20 minutes until 60 minutes. The pain score reduction at alltime intervals measured post-treatment were highly significant (P <0.001). No adverse events or vital signs deterioration observed following nebulized fentanyl. Conclusion: Nebulized fentanyl citrate at dose of 4 mcg/kg given through oxygen drive nebulizer circuit was effective in treating children with acute severe pain without causing adverse events and should be considered as a modality of acute pain treatment in children population. 2018 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/47846/1/Dr.%20Raden%20Nazerul%20Raden%20Yahaya-24%20pages.pdf Yahaya, Raden Nezarul Raden (2018) Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RD Surgery
spellingShingle RD Surgery
Yahaya, Raden Nezarul Raden
Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
description Introduction: To assess the effectiveness of nebulized fentanyl citrate in treating children presenting with acute severe pain of various aetiologies. Methods: Patients aged 5 to 15 years old presented with acute severe pain of any causes were enrolled into the study through convenient sampling and received intravenous preparation of fentanyl citrate at dose of 4 mcg/kg administered through oxygen driven nebulizer circuit. Pain scores were assessed at pre-treatment and subsequently at 5 minutes interval until 60 minutes post-treatment using Wong and Baker faces pain scale. Vital signs and potential adverse events were also monitored. Results: 42 children with acute pain of various causes participated in this study and tolerated the nebulized fentanyl citrate well. 2 patients were withdrawn due to insufficient pain control post treatment. The pain aetiologies were categorized into fractures (n=14), soft tissue injuries (n=15) and abdominal pain (n=11). The mean pain score at 10 minutes on nebulized fentanyl administration decreased by 2.65 (95% CI 2.62 to 2.73) from the baseline. Pain score continued to decrease at 15 minutes (mean pain score difference 4.20; 95% CI 4.01 to 4.39) followed by a sustained plateau pain score at 20 minutes until 60 minutes. The pain score reduction at alltime intervals measured post-treatment were highly significant (P <0.001). No adverse events or vital signs deterioration observed following nebulized fentanyl. Conclusion: Nebulized fentanyl citrate at dose of 4 mcg/kg given through oxygen drive nebulizer circuit was effective in treating children with acute severe pain without causing adverse events and should be considered as a modality of acute pain treatment in children population.
format Thesis
author Yahaya, Raden Nezarul Raden
author_facet Yahaya, Raden Nezarul Raden
author_sort Yahaya, Raden Nezarul Raden
title Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_short Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_full Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_fullStr Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_full_unstemmed Study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
title_sort study on the effectivenss of nebulized fentanyl citrate as modality of analgesia in children with acute pain
publishDate 2018
url http://eprints.usm.my/47846/1/Dr.%20Raden%20Nazerul%20Raden%20Yahaya-24%20pages.pdf
http://eprints.usm.my/47846/
_version_ 1683231615820496896
score 13.211869

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