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Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI

Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Meth...

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Main Author: Kamarudin, Mohd Nazlin
Format: Thesis
Language:English
Published: 2018
Subjects:
RC Internal medicine
Online Access:http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf
http://eprints.usm.my/46504/
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spelling my.usm.eprints.46504 http://eprints.usm.my/46504/ Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI Kamarudin, Mohd Nazlin RC Internal medicine Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Methodology: 38 healthy volunteers were included in this prospective study. Diffusion tensor imaging (DTI) of the rotator cuff muscles (subscapularis, supraspinatus and infraspinatus muscles) was performed with single-shot spin-echo echo-planar imaging sequences in 16 and 32 diffusion directions. Three different b-values were selected for each diffusion direction: b-value 400 s/mm2, 600s/mm2 and 800s/mm2. Signal to noise ratio (SNR) was measured in each muscle at different b-values and number of diffusion direction, and average SNR were calculated. Statistical analysis was performed with one-way ANOVA and paired t-test. Mean and standard deviation were obtained for each DTI parameters, and level of significance was determined (p < 0.05). Results: The signal to noise ratio was highest for all three muscles at b-value 400s/mm2 (subscapularis, 40.255; supraspinatus, 38.203; and infraspinatus, 48.232) followed by b-value 600s/mm2 and 800s/mm2. The use of 32 number of diffusion directions had shown to improve SNR value compared to 16 diffusion directions (P<0.05). Conclusions: The optimal combination of b value and number of diffusion directions in DTI of rotator cuff muscles on 3.0 Tesla MRI is 400s/mm2 and 32 directions respectively. 2018 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf Kamarudin, Mohd Nazlin (2018) Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RC Internal medicine
spellingShingle RC Internal medicine
Kamarudin, Mohd Nazlin
Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
description Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Methodology: 38 healthy volunteers were included in this prospective study. Diffusion tensor imaging (DTI) of the rotator cuff muscles (subscapularis, supraspinatus and infraspinatus muscles) was performed with single-shot spin-echo echo-planar imaging sequences in 16 and 32 diffusion directions. Three different b-values were selected for each diffusion direction: b-value 400 s/mm2, 600s/mm2 and 800s/mm2. Signal to noise ratio (SNR) was measured in each muscle at different b-values and number of diffusion direction, and average SNR were calculated. Statistical analysis was performed with one-way ANOVA and paired t-test. Mean and standard deviation were obtained for each DTI parameters, and level of significance was determined (p < 0.05). Results: The signal to noise ratio was highest for all three muscles at b-value 400s/mm2 (subscapularis, 40.255; supraspinatus, 38.203; and infraspinatus, 48.232) followed by b-value 600s/mm2 and 800s/mm2. The use of 32 number of diffusion directions had shown to improve SNR value compared to 16 diffusion directions (P<0.05). Conclusions: The optimal combination of b value and number of diffusion directions in DTI of rotator cuff muscles on 3.0 Tesla MRI is 400s/mm2 and 32 directions respectively.
format Thesis
author Kamarudin, Mohd Nazlin
author_facet Kamarudin, Mohd Nazlin
author_sort Kamarudin, Mohd Nazlin
title Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_short Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_full Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_fullStr Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_full_unstemmed Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
title_sort diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 tesla mri
publishDate 2018
url http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf
http://eprints.usm.my/46504/
_version_ 1662755793379786752
score 13.211869

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