Cover Image

Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein

Antigen recognition by T cell receptor (TCR) induces intracellular signaling cascades leading to T cell activation, subsequently inducing cellular proliferation and various effector functions. Adaptor proteins play important roles in T cell signaling by creating nodes to recruit signaling proteins a...

Full description

Saved in:
Bibliographic Details
Main Author: Kong, Mei Suen
Format: Thesis
Language:English
Published: 2017
Subjects:
RS1-441 Pharmacy and materia medica
Online Access:http://eprints.usm.my/45399/1/KONG%20MEI%20SUEN.pdf
http://eprints.usm.my/45399/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.usm.eprints.45399
record_format eprints
spelling my.usm.eprints.45399 http://eprints.usm.my/45399/ Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein Kong, Mei Suen RS1-441 Pharmacy and materia medica Antigen recognition by T cell receptor (TCR) induces intracellular signaling cascades leading to T cell activation, subsequently inducing cellular proliferation and various effector functions. Adaptor proteins play important roles in T cell signaling by creating nodes to recruit signaling proteins and form signal complexes to regulate the direction of signaling. Casitas B-lineage lymphoma (Cbl)-interacting protein of 85 kDa (CIN85) is an adaptor protein, originally identified as a Cbl-binding protein, and was suggested to be involved in the internalization and degradation of receptors and kinases. Nevertheless, the physiological function of CIN85 in T cells is unknown. 2017-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45399/1/KONG%20MEI%20SUEN.pdf Kong, Mei Suen (2017) Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Kong, Mei Suen
Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein
description Antigen recognition by T cell receptor (TCR) induces intracellular signaling cascades leading to T cell activation, subsequently inducing cellular proliferation and various effector functions. Adaptor proteins play important roles in T cell signaling by creating nodes to recruit signaling proteins and form signal complexes to regulate the direction of signaling. Casitas B-lineage lymphoma (Cbl)-interacting protein of 85 kDa (CIN85) is an adaptor protein, originally identified as a Cbl-binding protein, and was suggested to be involved in the internalization and degradation of receptors and kinases. Nevertheless, the physiological function of CIN85 in T cells is unknown.
format Thesis
author Kong, Mei Suen
author_facet Kong, Mei Suen
author_sort Kong, Mei Suen
title Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein
title_short Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein
title_full Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein
title_fullStr Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein
title_full_unstemmed Negative Regulation Of T Cell Activation And Function By CIN85 Adaptor Protein
title_sort negative regulation of t cell activation and function by cin85 adaptor protein
publishDate 2017
url http://eprints.usm.my/45399/1/KONG%20MEI%20SUEN.pdf
http://eprints.usm.my/45399/
_version_ 1646011341142491136
score 13.211869

Similar Items