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Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves

Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and sti...

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Main Author: Farsi, Elham
Format: Thesis
Language:English
Published: 2017
Subjects:
L7-991 Education (General)
Online Access:http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf
http://eprints.usm.my/45376/
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spelling my.usm.eprints.45376 http://eprints.usm.my/45376/ Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves Farsi, Elham L7-991 Education (General) Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and stimulating inflammation, events of which cause vascular and tubular dysfunction. Animal models have demonstrated that cisplatin-induced renal toxicity is characterized by a rapid loss of glomerular filtration, polyuria, hyperkalemia, hypernatremia, and azotemia. Recently, much attention has been given to the possible role of herbal medicine in protecting against cisplatin-induced renal toxicity. 2017-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf Farsi, Elham (2017) Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic L7-991 Education (General)
spellingShingle L7-991 Education (General)
Farsi, Elham
Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
description Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and stimulating inflammation, events of which cause vascular and tubular dysfunction. Animal models have demonstrated that cisplatin-induced renal toxicity is characterized by a rapid loss of glomerular filtration, polyuria, hyperkalemia, hypernatremia, and azotemia. Recently, much attention has been given to the possible role of herbal medicine in protecting against cisplatin-induced renal toxicity.
format Thesis
author Farsi, Elham
author_facet Farsi, Elham
author_sort Farsi, Elham
title Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_short Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_full Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_fullStr Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_full_unstemmed Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_sort nephroprotective effect of clinacanhus nutans, orthosiphon stamineus, and syzyguim camponulatum leaves against cisplatin-induced nephrotoxcity; and safety asseement of clinacathus nutans leaves
publishDate 2017
url http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf
http://eprints.usm.my/45376/
_version_ 1646011334752468992
score 13.223943

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