Cover Image

The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells

Cancer stem cells (CSCs) represent a small subpopulation within a tumour that possesses the stem-like properties but are also initiating resistance towards cytotoxic agent which contribute to cancer relapse. A natural compound such as curcumin that contains high polyphenol has been found to possess...

Full description

Saved in:
Bibliographic Details
Main Author: Nazilah, Abdul Satar
Format: Thesis
Language:English
Published: 2018
Subjects:
R735-854 Medical education. Medical schools. Research
Online Access:http://eprints.usm.my/45013/1/NAZILAH%20ABDUL%20SATAR.pdf
http://eprints.usm.my/45013/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.usm.eprints.45013
record_format eprints
spelling my.usm.eprints.45013 http://eprints.usm.my/45013/ The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells Nazilah, Abdul Satar R735-854 Medical education. Medical schools. Research Cancer stem cells (CSCs) represent a small subpopulation within a tumour that possesses the stem-like properties but are also initiating resistance towards cytotoxic agent which contribute to cancer relapse. A natural compound such as curcumin that contains high polyphenol has been found to possess chemo-sensitivity effect with an ability to sensitise the CSCs to the cytotoxic agents such as cisplatin. Therefore, the present study was designed to investigate the efficiency of curcumin as a chemo-sensitiser in lung CSCs and to analyse its inhibitory effect on CSCs activity using A549 and H2170 cell lines that belong to non-small cell lung cancer (NSCLC). 2018-09 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45013/1/NAZILAH%20ABDUL%20SATAR.pdf Nazilah, Abdul Satar (2018) The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells. PhD thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R735-854 Medical education. Medical schools. Research
spellingShingle R735-854 Medical education. Medical schools. Research
Nazilah, Abdul Satar
The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells
description Cancer stem cells (CSCs) represent a small subpopulation within a tumour that possesses the stem-like properties but are also initiating resistance towards cytotoxic agent which contribute to cancer relapse. A natural compound such as curcumin that contains high polyphenol has been found to possess chemo-sensitivity effect with an ability to sensitise the CSCs to the cytotoxic agents such as cisplatin. Therefore, the present study was designed to investigate the efficiency of curcumin as a chemo-sensitiser in lung CSCs and to analyse its inhibitory effect on CSCs activity using A549 and H2170 cell lines that belong to non-small cell lung cancer (NSCLC).
format Thesis
author Nazilah, Abdul Satar
author_facet Nazilah, Abdul Satar
author_sort Nazilah, Abdul Satar
title The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells
title_short The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells
title_full The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells
title_fullStr The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells
title_full_unstemmed The Chemo-Sensitisation Effect Of Curcumin Against Low Dose Cisplatin On Non-Small Cell Lung Cancer (NSCLC) Stem Cells
title_sort chemo-sensitisation effect of curcumin against low dose cisplatin on non-small cell lung cancer (nsclc) stem cells
publishDate 2018
url http://eprints.usm.my/45013/1/NAZILAH%20ABDUL%20SATAR.pdf
http://eprints.usm.my/45013/
_version_ 1643711168397705216
score 13.211869

Similar Items