Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion For Topical Delivery Of Ketoprofen
In this study emulsions with varying ratios of surfactant or its mixtures (Tween 80®, Tween 85® and Span 20®) were prepared using POE as the oil phase. The transparency of the mixtures was used as visual indications that nano-emulsions were formed and were reconfirmed by measuring the droplets si...
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my.usm.eprints.42298 http://eprints.usm.my/42298/ Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion For Topical Delivery Of Ketoprofen Sakeena, Mohamed Hameem Fatima RS1-441 Pharmacy and materia medica In this study emulsions with varying ratios of surfactant or its mixtures (Tween 80®, Tween 85® and Span 20®) were prepared using POE as the oil phase. The transparency of the mixtures was used as visual indications that nano-emulsions were formed and were reconfirmed by measuring the droplets size using laser scattering spectroscopy (Nanophox). The gel area of the triangle phase diagrams produced was used as one of criteria to determine the suitable HLB value of the nano-emulsion’s emulsifier for POE and for selection of several promising formulae. It was noted that largest gel area produced by HLB 15, 13.72 and 12. From these three phase diagrams three common points namely A, B and C were selected and mixtures of POE and surfactant constituted in them were used to study the solubility of ketoprofen. 2010-05 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42298/1/MOHAMED_HAMEEM_FATIMA_SAKEENA24.pdf Sakeena, Mohamed Hameem Fatima (2010) Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion For Topical Delivery Of Ketoprofen. Masters thesis, Universiti Sains Malaysia. |
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RS1-441 Pharmacy and materia medica Sakeena, Mohamed Hameem Fatima Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion For Topical Delivery Of Ketoprofen |
| description |
In this study emulsions with varying ratios of surfactant or its mixtures (Tween 80®,
Tween 85® and Span 20®) were prepared using POE as the oil phase. The
transparency of the mixtures was used as visual indications that nano-emulsions were
formed and were reconfirmed by measuring the droplets size using laser scattering
spectroscopy (Nanophox). The gel area of the triangle phase diagrams produced was
used as one of criteria to determine the suitable HLB value of the nano-emulsion’s
emulsifier for POE and for selection of several promising formulae. It was noted that
largest gel area produced by HLB 15, 13.72 and 12. From these three phase diagrams
three common points namely A, B and C were selected and mixtures of POE and
surfactant constituted in them were used to study the solubility of ketoprofen. |
| format |
Thesis |
| author |
Sakeena, Mohamed Hameem Fatima |
| author_facet |
Sakeena, Mohamed Hameem Fatima |
| author_sort |
Sakeena, Mohamed Hameem Fatima |
| title |
Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion
For Topical Delivery Of Ketoprofen
|
| title_short |
Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion
For Topical Delivery Of Ketoprofen
|
| title_full |
Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion
For Topical Delivery Of Ketoprofen
|
| title_fullStr |
Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion
For Topical Delivery Of Ketoprofen
|
| title_full_unstemmed |
Formulation And Evaluation Of Palm Oil Esters Based Nanoemulsion
For Topical Delivery Of Ketoprofen
|
| title_sort |
formulation and evaluation of palm oil esters based nanoemulsion
for topical delivery of ketoprofen |
| publishDate |
2010 |
| url |
http://eprints.usm.my/42298/1/MOHAMED_HAMEEM_FATIMA_SAKEENA24.pdf http://eprints.usm.my/42298/ |
| _version_ |
1643710465101004800 |
| score |
13.244404 |