Staff View: Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats

Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats

Little information exists about the effects of swimming exercise on bone health in ovariectomized animals with estrogen deficiency, which resembles the postmenopausal state and age-related bone loss in humans. This study investigated the effects of swimming exercise on tibia and femur bone mineral...

Full description

Saved in:

Bibliographic Details
Main Authors:	Foong, Kiew Ooi, Norsyam, Wan Mohd, Ghosh, Asok Kumar, Sulaiman, Siti Amrah, Chee, Keong Chen, Hung, Leung Kim
Format:	Article
Published:	Elsevier 2014
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://eprints.usm.my/38905/ https://doi.org/10.1016/j.jesf.2014.09.001
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.usm.eprints.38905
record_format	eprints
spelling	my.usm.eprints.38905 http://eprints.usm.my/38905/ Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim RM Therapeutics. Pharmacology Little information exists about the effects of swimming exercise on bone health in ovariectomized animals with estrogen deficiency, which resembles the postmenopausal state and age-related bone loss in humans. This study investigated the effects of swimming exercise on tibia and femur bone mineral density (BMD), geometry, and microstructure in sham and ovariectomized rats. Forty 3-month-old female rats were divided into four groups: sham operated-sedentary control (Sham-control), sham operated with swimming exercise group (Sham-Swim), ovariectomysedentary control (OVx-control), and ovariectomy and swimming exercise (OVx-Swim) groups. Swimming sessions were performed by the rats 90 minutes/day for 5 days/week for a total of 8 weeks. At the end of the study, tibial and femoral proximal volumetric total BMD, midshaft cortical volumetric BMD, cross-sectional area, and cross-sectional moment of inertia (MOI), and bone microstructural properties were measured for comparison. Data were analyzed using one-way analysis of variance (ANOVA). The Sham-Swim group exhibited significantly ( p < 0.05; one-way ANOVA) greater values in bone geometry parameters, that is, tibial midshaft cortical area and MOI compared to the Sham-control group. However, no significant differences were observed in these parameters between the Ovx-Swim and Ovx-control groups. There were no significant differences in femoral BMD between the Sham-Swim and Sham-control groups. Nevertheless, the Ovx-Swim group elicited significantly ( p < 0.05; one-way ANOVA) higher femoral proximal total BMD and improved bone microstructure compared to the Ovx-Sham group. In conclusion, the positive effects of swimming on bone properties in the ovariectomized rats in the present study may suggest that swimming as a non- or low-weight-bearing exercise may be beneficial for enhancing bone health in the postmenopausal population. Elsevier 2014-12 Article PeerReviewed Foong, Kiew Ooi and Norsyam, Wan Mohd and Ghosh, Asok Kumar and Sulaiman, Siti Amrah and Chee, Keong Chen and Hung, Leung Kim (2014) Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats. Journal of Exercise Science and Fitness, 12 (2). pp. 80-87. ISSN 1728-869X https://doi.org/10.1016/j.jesf.2014.09.001
institution	Universiti Sains Malaysia
building	Hamzah Sendut Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Sains Malaysia
content_source	USM Institutional Repository
url_provider	http://eprints.usm.my/
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
description	Little information exists about the effects of swimming exercise on bone health in ovariectomized animals with estrogen deficiency, which resembles the postmenopausal state and age-related bone loss in humans. This study investigated the effects of swimming exercise on tibia and femur bone mineral density (BMD), geometry, and microstructure in sham and ovariectomized rats. Forty 3-month-old female rats were divided into four groups: sham operated-sedentary control (Sham-control), sham operated with swimming exercise group (Sham-Swim), ovariectomysedentary control (OVx-control), and ovariectomy and swimming exercise (OVx-Swim) groups. Swimming sessions were performed by the rats 90 minutes/day for 5 days/week for a total of 8 weeks. At the end of the study, tibial and femoral proximal volumetric total BMD, midshaft cortical volumetric BMD, cross-sectional area, and cross-sectional moment of inertia (MOI), and bone microstructural properties were measured for comparison. Data were analyzed using one-way analysis of variance (ANOVA). The Sham-Swim group exhibited significantly ( p < 0.05; one-way ANOVA) greater values in bone geometry parameters, that is, tibial midshaft cortical area and MOI compared to the Sham-control group. However, no significant differences were observed in these parameters between the Ovx-Swim and Ovx-control groups. There were no significant differences in femoral BMD between the Sham-Swim and Sham-control groups. Nevertheless, the Ovx-Swim group elicited significantly ( p < 0.05; one-way ANOVA) higher femoral proximal total BMD and improved bone microstructure compared to the Ovx-Sham group. In conclusion, the positive effects of swimming on bone properties in the ovariectomized rats in the present study may suggest that swimming as a non- or low-weight-bearing exercise may be beneficial for enhancing bone health in the postmenopausal population.
format	Article
author	Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim
author_facet	Foong, Kiew Ooi Norsyam, Wan Mohd Ghosh, Asok Kumar Sulaiman, Siti Amrah Chee, Keong Chen Hung, Leung Kim
author_sort	Foong, Kiew Ooi
title	Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
title_short	Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
title_full	Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
title_fullStr	Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
title_full_unstemmed	Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
title_sort	effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats
publisher	Elsevier
publishDate	2014
url	http://eprints.usm.my/38905/ https://doi.org/10.1016/j.jesf.2014.09.001
_version_	1643709494751920128
score	13.211869

Effects of short-term swimming exercise on bone mineral density, geometry, and microstructural properties in sham and ovariectomized rats

Similar Items