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Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression

The data presented in this article are related to the research article entitled “The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (IKr) and human ether-a-go-go-related gene (hERG) expression” (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaiman...

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Main Authors: Yi, Fan Teah, Abduraman, Muhammad Asyraf, Amanah, Azimah, Adenan, Mohd Ilham, Sulaiman, Shaida Fariza, Mei, Lan Tan
Format: Article
Language:English
Published: Elsevier 2017
Subjects:
QH1 Natural history (General - Including nature conservation, geographical distribution)
RK1-715 Dentistry
Online Access:http://eprints.usm.my/38611/1/Data_on_the_construction_of_a_recombinant_HEK293_cell_line_overexpressing_hERG.pdf
http://eprints.usm.my/38611/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574817/
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spelling my.usm.eprints.38611 http://eprints.usm.my/38611/ Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression Yi, Fan Teah Abduraman, Muhammad Asyraf Amanah, Azimah Adenan, Mohd Ilham Sulaiman, Shaida Fariza Mei, Lan Tan QH1 Natural history (General - Including nature conservation, geographical distribution) RK1-715 Dentistry The data presented in this article are related to the research article entitled “The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (IKr) and human ether-a-go-go-related gene (hERG) expression” (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaiman, M.L. Tan) [1], which the possible hERG blocking properties of deoxyelephantopin were investigated. This article describes the construction of human embryonic kidney 293 (HEK293) cells overexpressing HERG potassium channel and verification of the presence of hERG mRNA and protein expression in this recombinant cell line. Elsevier 2017 Article PeerReviewed application/pdf en http://eprints.usm.my/38611/1/Data_on_the_construction_of_a_recombinant_HEK293_cell_line_overexpressing_hERG.pdf Yi, Fan Teah and Abduraman, Muhammad Asyraf and Amanah, Azimah and Adenan, Mohd Ilham and Sulaiman, Shaida Fariza and Mei, Lan Tan (2017) Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression. Data in Brief, 14. pp. 584-591. ISSN 2352-3409 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574817/
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic QH1 Natural history (General - Including nature conservation, geographical distribution)
RK1-715 Dentistry
spellingShingle QH1 Natural history (General - Including nature conservation, geographical distribution)
RK1-715 Dentistry
Yi, Fan Teah
Abduraman, Muhammad Asyraf
Amanah, Azimah
Adenan, Mohd Ilham
Sulaiman, Shaida Fariza
Mei, Lan Tan
Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
description The data presented in this article are related to the research article entitled “The effects of deoxyelephantopin on the cardiac delayed rectifier potassium channel current (IKr) and human ether-a-go-go-related gene (hERG) expression” (Y.F. Teah, M.A. Abduraman, A. Amanah, M.I. Adenan, S.F. Sulaiman, M.L. Tan) [1], which the possible hERG blocking properties of deoxyelephantopin were investigated. This article describes the construction of human embryonic kidney 293 (HEK293) cells overexpressing HERG potassium channel and verification of the presence of hERG mRNA and protein expression in this recombinant cell line.
format Article
author Yi, Fan Teah
Abduraman, Muhammad Asyraf
Amanah, Azimah
Adenan, Mohd Ilham
Sulaiman, Shaida Fariza
Mei, Lan Tan
author_facet Yi, Fan Teah
Abduraman, Muhammad Asyraf
Amanah, Azimah
Adenan, Mohd Ilham
Sulaiman, Shaida Fariza
Mei, Lan Tan
author_sort Yi, Fan Teah
title Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_short Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_full Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_fullStr Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_full_unstemmed Data on the construction of a recombinant HEK293 cell line overexpressing hERG potassium channel and examining the presence of hERG mRNA and protein expression
title_sort data on the construction of a recombinant hek293 cell line overexpressing herg potassium channel and examining the presence of herg mrna and protein expression
publisher Elsevier
publishDate 2017
url http://eprints.usm.my/38611/1/Data_on_the_construction_of_a_recombinant_HEK293_cell_line_overexpressing_hERG.pdf
http://eprints.usm.my/38611/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574817/
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score 13.211869

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