The role of REST and HDAC2 in epigenetic dysregulation of Nav1.5 and nNav1.5 expression in breast cancer
Background: Increased expression of voltage-gated sodium channels (VGSCs) have been implicated with strong metastatic potential of human breast cancer in vitro and in vivo where the main culprits are cardiac isoform Nav1.5 and its ‘neonatal’ splice variant, nNav1.5. Several factors have been assoc...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BioMed Central
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/38047/1/4th_paper_2017.pdf http://eprints.usm.my/38047/ https://cancerci.biomedcentral.com/articles/10.1186/s12935-017-0442-6 |
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