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Evaluation of Medication Use in Malaysian Predialysis Patients

Chronic kidney disease (CKD) patients suffer from multiple comorbidities and complications as a cause or consequence of kidney disease. Information regarding medicationprescribing patterns in predialysis patients is sparse. We conducted a retrospective study to evaluate the medication prescriptio...

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Main Authors:	Muhammad Salman, Muhammad Salman, Khan, Amer Hayat, Adnan, Azreen Syazril, Syed Sulaiman, Syed Azhar, Shehzadi, Naureen, Asif, Nauman, Hussain, Khalid, Saleem, Fahad, Raza, Muhammed Hussnain, Farooq, Muhammad Shahid
Format:	Article
Language:	English
Published:	Medknow Publications 2017
Subjects:	R Medicine (General) RS Pharmacy and materia medica
Online Access:	http://eprints.usm.my/36928/1/%28Evaluation_of_medication_use%29_SaudiJKidneyDisTranspl283517-7557673_205936.pdf http://eprints.usm.my/36928/ http://www.sjkdt.org/text.asp?2017/28/3/517/206451
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id	my.usm.eprints.36928
record_format	eprints
spelling	my.usm.eprints.36928 http://eprints.usm.my/36928/ Evaluation of Medication Use in Malaysian Predialysis Patients Muhammad Salman, Muhammad Salman Khan, Amer Hayat Adnan, Azreen Syazril Syed Sulaiman, Syed Azhar Shehzadi, Naureen Asif, Nauman Hussain, Khalid Saleem, Fahad Raza, Muhammed Hussnain Farooq, Muhammad Shahid R Medicine (General) RS Pharmacy and materia medica Chronic kidney disease (CKD) patients suffer from multiple comorbidities and complications as a cause or consequence of kidney disease. Information regarding medicationprescribing patterns in predialysis patients is sparse. We conducted a retrospective study to evaluate the medication prescription patterns among predialysis patients. Medical records (both paper based and computerized) of patients at CKD Resource Centre, Hospital Universiti Sains Malaysia, were reviewed. A total of 615 eligible cases were included in the study. The mean number of medications prescribed per patient was 8.22 ± 2.81, and medication use was correlated to the renal function (stage 3a < stage 3b < stage 4 < stage 5; P <0.001). The top three prescribed medication groups were found to be lipid-lowering agents, calcium channel blockers, and antiplatelet agents. Some medication classes such as nonaluminum/noncalcium phosphate binders, erythropoietin-stimulating agents, and renin-angiotensin-aldosterone system blockers, particularly in advanced stage, were found to be underutilized. In conclusion, predialysis patients are prescribed a large number of medications. Our findings highlight the need for assessing the impact of current medication-prescribing patterns on morbidity and mortality rates in Malaysian predialysis population. Medknow Publications 2017 Article PeerReviewed application/pdf en http://eprints.usm.my/36928/1/%28Evaluation_of_medication_use%29_SaudiJKidneyDisTranspl283517-7557673_205936.pdf Muhammad Salman, Muhammad Salman and Khan, Amer Hayat and Adnan, Azreen Syazril and Syed Sulaiman, Syed Azhar and Shehzadi, Naureen and Asif, Nauman and Hussain, Khalid and Saleem, Fahad and Raza, Muhammed Hussnain and Farooq, Muhammad Shahid (2017) Evaluation of Medication Use in Malaysian Predialysis Patients. Saudi Journal of Kidney Diseases and Transplantation, 28 (3). pp. 517-523. ISSN 1319-2442 http://www.sjkdt.org/text.asp?2017/28/3/517/206451
institution	Universiti Sains Malaysia
building	Hamzah Sendut Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Sains Malaysia
content_source	USM Institutional Repository
url_provider	http://eprints.usm.my/
language	English
topic	R Medicine (General) RS Pharmacy and materia medica
spellingShingle	R Medicine (General) RS Pharmacy and materia medica Muhammad Salman, Muhammad Salman Khan, Amer Hayat Adnan, Azreen Syazril Syed Sulaiman, Syed Azhar Shehzadi, Naureen Asif, Nauman Hussain, Khalid Saleem, Fahad Raza, Muhammed Hussnain Farooq, Muhammad Shahid Evaluation of Medication Use in Malaysian Predialysis Patients
description	Chronic kidney disease (CKD) patients suffer from multiple comorbidities and complications as a cause or consequence of kidney disease. Information regarding medicationprescribing patterns in predialysis patients is sparse. We conducted a retrospective study to evaluate the medication prescription patterns among predialysis patients. Medical records (both paper based and computerized) of patients at CKD Resource Centre, Hospital Universiti Sains Malaysia, were reviewed. A total of 615 eligible cases were included in the study. The mean number of medications prescribed per patient was 8.22 ± 2.81, and medication use was correlated to the renal function (stage 3a < stage 3b < stage 4 < stage 5; P <0.001). The top three prescribed medication groups were found to be lipid-lowering agents, calcium channel blockers, and antiplatelet agents. Some medication classes such as nonaluminum/noncalcium phosphate binders, erythropoietin-stimulating agents, and renin-angiotensin-aldosterone system blockers, particularly in advanced stage, were found to be underutilized. In conclusion, predialysis patients are prescribed a large number of medications. Our findings highlight the need for assessing the impact of current medication-prescribing patterns on morbidity and mortality rates in Malaysian predialysis population.
format	Article
author	Muhammad Salman, Muhammad Salman Khan, Amer Hayat Adnan, Azreen Syazril Syed Sulaiman, Syed Azhar Shehzadi, Naureen Asif, Nauman Hussain, Khalid Saleem, Fahad Raza, Muhammed Hussnain Farooq, Muhammad Shahid
author_facet	Muhammad Salman, Muhammad Salman Khan, Amer Hayat Adnan, Azreen Syazril Syed Sulaiman, Syed Azhar Shehzadi, Naureen Asif, Nauman Hussain, Khalid Saleem, Fahad Raza, Muhammed Hussnain Farooq, Muhammad Shahid
author_sort	Muhammad Salman, Muhammad Salman
title	Evaluation of Medication Use in Malaysian Predialysis Patients
title_short	Evaluation of Medication Use in Malaysian Predialysis Patients
title_full	Evaluation of Medication Use in Malaysian Predialysis Patients
title_fullStr	Evaluation of Medication Use in Malaysian Predialysis Patients
title_full_unstemmed	Evaluation of Medication Use in Malaysian Predialysis Patients
title_sort	evaluation of medication use in malaysian predialysis patients
publisher	Medknow Publications
publishDate	2017
url	http://eprints.usm.my/36928/1/%28Evaluation_of_medication_use%29_SaudiJKidneyDisTranspl283517-7557673_205936.pdf http://eprints.usm.my/36928/ http://www.sjkdt.org/text.asp?2017/28/3/517/206451
_version_	1643708925344743424
score	13.211869

Evaluation of Medication Use in Malaysian Predialysis Patients

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