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Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage

Fagositosis oleh makrofaj adalah mekanisme pertahanan pertama terhadap jangkitan parasit malaria dalam sistem imun semula jadi. Setelah diaktifkan, makrofaj akan bertindak sebagai sel radang dan sel anti-mikrob melalui rembesan sitokin pro-inflamatori dan nitrik oksida (NO). Dalam kajian ini, kesan...

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Main Author: Mohamad, Dhaniah
Format: Thesis
Language:English
Published: 2013
Subjects:
R5-130.5 General works
Online Access:http://eprints.usm.my/36407/1/Dr._Dhaniah_Mohamad_TSTZ_%28NN24%29.pdf
http://eprints.usm.my/36407/
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spelling my.usm.eprints.36407 http://eprints.usm.my/36407/ Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage Mohamad, Dhaniah R5-130.5 General works Fagositosis oleh makrofaj adalah mekanisme pertahanan pertama terhadap jangkitan parasit malaria dalam sistem imun semula jadi. Setelah diaktifkan, makrofaj akan bertindak sebagai sel radang dan sel anti-mikrob melalui rembesan sitokin pro-inflamatori dan nitrik oksida (NO). Dalam kajian ini, kesan immunoregulatori klon BCG rekombinan (rBCG) yang mengekspreskan terminus C protein permukaan merozoite-1 19-kDa (MSP-1C) daripada Plasmodium falciparum ke atas sel makrofaj mencit, J774A.1 telah dikaji. Macrophage phagocytosis acts as the first line of defence against malaria parasites infection in the innate immune system. Once activated, macrophages act as inflammatory and microbicidal cells through the production of pro-inflammatory cytokines and nitric oxide (NO). In this study, the immunoregulatory effects of a recombinant BCG (rBCG) clone expressing the 19-kDa C-terminus of the merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum was examined on the mouse macrophage cell line J774A.1. 2013-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/36407/1/Dr._Dhaniah_Mohamad_TSTZ_%28NN24%29.pdf Mohamad, Dhaniah (2013) Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage. Masters thesis, Universiti Sains Malaysia.
institution Universiti Sains Malaysia
building Hamzah Sendut Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
url_provider http://eprints.usm.my/
language English
topic R5-130.5 General works
spellingShingle R5-130.5 General works
Mohamad, Dhaniah
Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage
description Fagositosis oleh makrofaj adalah mekanisme pertahanan pertama terhadap jangkitan parasit malaria dalam sistem imun semula jadi. Setelah diaktifkan, makrofaj akan bertindak sebagai sel radang dan sel anti-mikrob melalui rembesan sitokin pro-inflamatori dan nitrik oksida (NO). Dalam kajian ini, kesan immunoregulatori klon BCG rekombinan (rBCG) yang mengekspreskan terminus C protein permukaan merozoite-1 19-kDa (MSP-1C) daripada Plasmodium falciparum ke atas sel makrofaj mencit, J774A.1 telah dikaji. Macrophage phagocytosis acts as the first line of defence against malaria parasites infection in the innate immune system. Once activated, macrophages act as inflammatory and microbicidal cells through the production of pro-inflammatory cytokines and nitric oxide (NO). In this study, the immunoregulatory effects of a recombinant BCG (rBCG) clone expressing the 19-kDa C-terminus of the merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum was examined on the mouse macrophage cell line J774A.1.
format Thesis
author Mohamad, Dhaniah
author_facet Mohamad, Dhaniah
author_sort Mohamad, Dhaniah
title Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage
title_short Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage
title_full Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage
title_fullStr Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage
title_full_unstemmed Immunoregulatory effects of recombinant BCG (rBCG) expressing c-terminus of merozoite surface protein-1 (MSP-1C) of Plasmodium falciparum on mouse macrophage
title_sort immunoregulatory effects of recombinant bcg (rbcg) expressing c-terminus of merozoite surface protein-1 (msp-1c) of plasmodium falciparum on mouse macrophage
publishDate 2013
url http://eprints.usm.my/36407/1/Dr._Dhaniah_Mohamad_TSTZ_%28NN24%29.pdf
http://eprints.usm.my/36407/
_version_ 1643708774580486144
score 13.211869

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