Rapid Screening for C3435t Polymorphism in Exon 26 of the Multi-Drug Resistance (MDR1) Gene in Malay Patients with Acute Leukemia
The over expression of P-glycoprotein has been found to be associated with therapy resistance in hematological malignancies including acute leukemias. Recently, a single nucleotide polymorphism (SNP) in exon 26 (C3435T) in the MDR1 gene has shown to have functional consequences with altered expre...
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Format: | Article |
Language: | English |
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Penerbit Universiti Sains Malaysia
2005
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Online Access: | http://eprints.usm.my/29260/1/badrulyahaya2005.pdf http://eprints.usm.my/29260/ http://journal.usm.my/journal/10th%20ncms%20oral%20-%20supp%202005.pdf |
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