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Hepatitis C and kidney disease: An overview and approach to management

Hepatitis C infection and chronic kidney disease are major health burden worldwide. Hepatitis C infection is associated with a wide range of extra-hepatic manifestations in various organs including the kidneys. A strong association between hepatitis C and chronic kidney disease has come to light. He...

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Main Authors: A.N., Azmi,, Tan, S.-S.,, Mohamed, R.,
Format: Article
Language:en_US
Published: Baishideng Publishing Group Co 2015
Subjects:
Chronic hepatitis C
Kidney disease
Management
Online Access:http://ddms.usim.edu.my/handle/123456789/8823
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spelling my.usim-88232017-02-23T07:19:40Z Hepatitis C and kidney disease: An overview and approach to management A.N., Azmi, Tan, S.-S., Mohamed, R., Chronic hepatitis C Kidney disease Management Hepatitis C infection and chronic kidney disease are major health burden worldwide. Hepatitis C infection is associated with a wide range of extra-hepatic manifestations in various organs including the kidneys. A strong association between hepatitis C and chronic kidney disease has come to light. Hemodialysis in supporting the end stage renal disease patients unfortunately carries a risk for hepatitis C infection. Despite much improvement in the care of this group of patients, the prevalence of hepatitis C infection in hemodialysis patients is still higher than the general population. Hepatitis C infection has a negative effect on the survival of hemodialysis and renal transplant patients. Treatment of hepatitis C in end stage renal disease patients using conventional or pegylated interferon with or without ribavirin remains a clinical challenge with low response rate, high dropout rate due to poor tolerability and many unmet needs. The approval of new direct acting antiviral agents for hepatitis C may dramatically change the treatment approach in hepatitis C infected patients with mild to moderate renal impairment. However it remains to be confirmed if the newer Hepatitis C therapies are safe in individuals with severe renal impairment. This review article discusses the relationship between hepatitis C and chronic kidney disease, describe the various types of renal diseases associated with hepatitis C and the newer as well as the existing treatments for hepatitis C in the context of this subpopulation of hepatitis C patients. 2015-07-14T07:40:35Z 2015-07-14T07:40:35Z 2015 Article 19485182 http://ddms.usim.edu.my/handle/123456789/8823 en_US Baishideng Publishing Group Co
institution Universiti Sains Islam Malaysia
building USIM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universit Sains Islam i Malaysia
content_source USIM Institutional Repository
url_provider http://ddms.usim.edu.my/
language en_US
topic Chronic hepatitis C
Kidney disease
Management
spellingShingle Chronic hepatitis C
Kidney disease
Management
A.N., Azmi,
Tan, S.-S.,
Mohamed, R.,
Hepatitis C and kidney disease: An overview and approach to management
description Hepatitis C infection and chronic kidney disease are major health burden worldwide. Hepatitis C infection is associated with a wide range of extra-hepatic manifestations in various organs including the kidneys. A strong association between hepatitis C and chronic kidney disease has come to light. Hemodialysis in supporting the end stage renal disease patients unfortunately carries a risk for hepatitis C infection. Despite much improvement in the care of this group of patients, the prevalence of hepatitis C infection in hemodialysis patients is still higher than the general population. Hepatitis C infection has a negative effect on the survival of hemodialysis and renal transplant patients. Treatment of hepatitis C in end stage renal disease patients using conventional or pegylated interferon with or without ribavirin remains a clinical challenge with low response rate, high dropout rate due to poor tolerability and many unmet needs. The approval of new direct acting antiviral agents for hepatitis C may dramatically change the treatment approach in hepatitis C infected patients with mild to moderate renal impairment. However it remains to be confirmed if the newer Hepatitis C therapies are safe in individuals with severe renal impairment. This review article discusses the relationship between hepatitis C and chronic kidney disease, describe the various types of renal diseases associated with hepatitis C and the newer as well as the existing treatments for hepatitis C in the context of this subpopulation of hepatitis C patients.
format Article
author A.N., Azmi,
Tan, S.-S.,
Mohamed, R.,
author_facet A.N., Azmi,
Tan, S.-S.,
Mohamed, R.,
author_sort A.N., Azmi,
title Hepatitis C and kidney disease: An overview and approach to management
title_short Hepatitis C and kidney disease: An overview and approach to management
title_full Hepatitis C and kidney disease: An overview and approach to management
title_fullStr Hepatitis C and kidney disease: An overview and approach to management
title_full_unstemmed Hepatitis C and kidney disease: An overview and approach to management
title_sort hepatitis c and kidney disease: an overview and approach to management
publisher Baishideng Publishing Group Co
publishDate 2015
url http://ddms.usim.edu.my/handle/123456789/8823
_version_ 1645152480841957376
score 13.222552

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