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Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation

Electroencephalography (EEG) can directly monitor the temporal progression of cortical changes induced by repetitive Transcranial Magnetic Stimulation (rTMS) and facilitate the understanding of cortical and subcortical influences in the genesis of oscillations. In this combined rTMS/EEG study, we ai...

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Main Authors: Giorgio, Fuggetta,, Nor Azila, Noh,
Format: Article
Language:English
Published: Wiley-Blackwell 2015
Subjects:
Synaptic Plasticity
EEG-TMS Combination; Event-Related Power;
Event-Related Coherence
Motor Cortex
Oscillations
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spelling my.usim-82832015-12-31T03:20:23Z Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation Giorgio, Fuggetta, Nor Azila, Noh, Synaptic Plasticity EEG-TMS Combination; Event-Related Power; Event-Related Coherence Motor Cortex Oscillations Electroencephalography (EEG) can directly monitor the temporal progression of cortical changes induced by repetitive Transcranial Magnetic Stimulation (rTMS) and facilitate the understanding of cortical and subcortical influences in the genesis of oscillations. In this combined rTMS/EEG study, we aimed to investigate changes in oscillatory activity after high-frequency (similar to 11 Hz) rTMS relative to the number of applied pulses. Twenty intermittent trains of 20 or 60 rTMS pulses were delivered over the human primary motor cortex at rest and tuned to individual mu frequency. The regional and interregional oscillatory neural activity after stimulation were evaluated using event-related power (ERPow) and event-related coherence (ERCoh) transformations. The most prominent changes for ERPow were observed in the theta band (4-7 Hz), as an increase in ERPow up to 20 s following 60 rTMS pulses, whereas ERPow increases were smaller in mu (1012 Hz) and beta (1330 Hz). ERCoh revealed that rTMS 60 modulated the connectivity in the theta band for up to 20 s. The topography of mu and theta changes were not identical; mu was more focal and theta was more global. Our data suggested the presence of independent cortical theta and mu generators with different reactivity to rTMS but could not rule out possible thalamocortical contributions in generating theta and mu over the motor network. Hum Brain Mapp 33:2224-2237, 2012. (c) 2011 Wiley Periodicals, Inc. 2015-06-10T03:53:35Z 2015-06-10T03:53:35Z 2012 Article 1065-9471 en Wiley-Blackwell
institution Universiti Sains Islam Malaysia
building USIM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universit Sains Islam i Malaysia
content_source USIM Institutional Repository
url_provider http://ddms.usim.edu.my/
language English
topic Synaptic Plasticity
EEG-TMS Combination; Event-Related Power;
Event-Related Coherence
Motor Cortex
Oscillations
spellingShingle Synaptic Plasticity
EEG-TMS Combination; Event-Related Power;
Event-Related Coherence
Motor Cortex
Oscillations
Giorgio, Fuggetta,
Nor Azila, Noh,
Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation
description Electroencephalography (EEG) can directly monitor the temporal progression of cortical changes induced by repetitive Transcranial Magnetic Stimulation (rTMS) and facilitate the understanding of cortical and subcortical influences in the genesis of oscillations. In this combined rTMS/EEG study, we aimed to investigate changes in oscillatory activity after high-frequency (similar to 11 Hz) rTMS relative to the number of applied pulses. Twenty intermittent trains of 20 or 60 rTMS pulses were delivered over the human primary motor cortex at rest and tuned to individual mu frequency. The regional and interregional oscillatory neural activity after stimulation were evaluated using event-related power (ERPow) and event-related coherence (ERCoh) transformations. The most prominent changes for ERPow were observed in the theta band (4-7 Hz), as an increase in ERPow up to 20 s following 60 rTMS pulses, whereas ERPow increases were smaller in mu (1012 Hz) and beta (1330 Hz). ERCoh revealed that rTMS 60 modulated the connectivity in the theta band for up to 20 s. The topography of mu and theta changes were not identical; mu was more focal and theta was more global. Our data suggested the presence of independent cortical theta and mu generators with different reactivity to rTMS but could not rule out possible thalamocortical contributions in generating theta and mu over the motor network. Hum Brain Mapp 33:2224-2237, 2012. (c) 2011 Wiley Periodicals, Inc.
format Article
author Giorgio, Fuggetta,
Nor Azila, Noh,
author_facet Giorgio, Fuggetta,
Nor Azila, Noh,
author_sort Giorgio, Fuggetta,
title Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation
title_short Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation
title_full Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation
title_fullStr Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation
title_full_unstemmed Human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation
title_sort human cortical theta reactivity to high-frequency repetitive transcranial magnetic stimulation
publisher Wiley-Blackwell
publishDate 2015
_version_ 1645152385213923328
score 13.222552

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