A single inhibitory upstream open reading frame (uORF) is sufficient to regulate Candida albicans GCN4 translation in response to amino acid starvation conditions

Candida albicans is a major fungal pathogen that responds to various environmental cues as part of its infection mechanism. We show here that the expression of C. albicans GCN4, which encodes a transcription factor that regulates morphogenetic and metabolic responses, is translationally regulated in...

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Main Authors: Arunkumar, Sundaram,, Chris M., Grant,
格式: Article
语言:English
出版: Cold Spring Harbor Lab Press, Publications Dept 2015
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