Mitochondrial redox modulation of NLRP3 inflammasome in differentiated THP-1 cells
Introduction: Innate host defence against pathogen required NLRP3 inflammasome activation. Two steps of inflammasome complex activation are identified: Signal 1 or priming (expression of NLRP3 protein, pro-IL-1β, pro-IL-18 and pro-caspase-1), followed by Signal 2 or activation (expression of active...
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| Main Authors: | , , |
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| Format: | Article |
| Published: |
Universiti Putra Malaysia
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/99040/ https://medic.upm.edu.my/jurnal_kami/volume_15_2019/mjmhs_vol_15_supplement_7_november_2019-53935 |
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