Identification of potential riboflavin synthase inhibitors by virtual screening and molecular dynamics simulation studies
Riboflavin synthase is an important enzyme catalyzing the last step of riboflavin biosynthesis in microorganisms. Due to the absolute dependency of the microbes to this biosynthetic pathway coupled with its nonexistence in humans, riboflavin synthase (RiS) is considered as a prospective drug target....
Saved in:
Main Authors: | Mohamad Aris, Sayangku Nor Ariati, Abdul Rahman, Mohd Zulhilmi, Raja Abd Rahman, Raja Noor Zaliha, Mohamad Ali, Mohd Shukuri, Salleh, Abu Bakar, Teo, Chian Ying, Leow, Adam Thean Chor |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021
|
Online Access: | http://psasir.upm.edu.my/id/eprint/97605/1/ABSTRACT.pdf http://psasir.upm.edu.my/id/eprint/97605/ https://www.sciencedirect.com/science/article/pii/S1018364720303839 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Unravelling the structure of riboflavin synthase from Leptospira kmetyi for designing potential anti-bacterial drug
by: Mohamad Aris, Sayangku Nor Ariati
Published: (2021) -
Unraveling the crystal structure of Leptospira kmetyi riboflavin synthase and computational analyses for potential development of new antibacterials
by: Mohamad Aris, Sayangku Nor Ariati, et al.
Published: (2022) -
Virtual screening for ganodermal polyketide synthases inhibitor
by: Ong, Chia Sui, et al.
Published: (2017) -
Involvement of a flavoprotein, acetohydroxyacid synthase, in growth and riboflavin production in riboflavin-overproducing Ashbya gossypii mutant
by: Kato, Tatsuya, et al.
Published: (2023) -
Ligand-based virtual screening for the discovery of inhibitors for protein arginine deiminase type 4 (PAD4)
by: Teo, Chian Ying, et al.
Published: (2013)