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Discovery of new inhibitor for the protein arginine deiminase type 4 (PAD4) by rational design of α-enolase-derived peptides

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting about 0.24 % of the world population. Protein arginine deiminase type 4 (PAD4) is believed to be responsible for the occurrence of RA by catalyzing citrullination of proteins. The citrullinated proteins act as autoantigens by...

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Bibliographic Details
Main Authors: Ahmad Nadzirin, Izzuddin, Leow, Adam Thean Chor, Salleh, Abu Bakar, Abdul Rahman, Mohd Basyaruddin, Tejo, Bimo Ario
Format: Article
Language:English
Published: Elsevier 2021
Online Access:http://psasir.upm.edu.my/id/eprint/96755/1/ABSTRACT.pdf
http://psasir.upm.edu.my/id/eprint/96755/
https://www.sciencedirect.com/science/article/pii/S1476927121000542
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http://psasir.upm.edu.my/id/eprint/96755/1/ABSTRACT.pdf
http://psasir.upm.edu.my/id/eprint/96755/
https://www.sciencedirect.com/science/article/pii/S1476927121000542

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