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Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment

This study aims to examine the efficacy of mosquito mat vaporizers on Aedes aegypti and their associated metabolic detoxication mechanisms. For this purpose, Aedes aegypti (Linnaeus) was collected from nine districts in Selangor, Malaysia and tested with mosquito vaporizing mat bioassays. The same p...

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Main Authors: Taib, Azratul Hizayu, Chen, Chee Dhang, Lau, K. W., Abdul Wahid, Noor Azrizal, Tan, Tiong Kai, Lim, Yvonne Ai Lian, Azirun, Mohd Sofian, Low, Van Lun
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Published: Malaysian Society of Parasitology and Tropical Medicine 2021
Online Access:http://psasir.upm.edu.my/id/eprint/96224/
https://msptm.org/vol-38-no-3-september/
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spelling my.upm.eprints.962242023-02-13T07:30:39Z http://psasir.upm.edu.my/id/eprint/96224/ Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment Taib, Azratul Hizayu Chen, Chee Dhang Lau, K. W. Abdul Wahid, Noor Azrizal Tan, Tiong Kai Lim, Yvonne Ai Lian Azirun, Mohd Sofian Low, Van Lun This study aims to examine the efficacy of mosquito mat vaporizers on Aedes aegypti and their associated metabolic detoxication mechanisms. For this purpose, Aedes aegypti (Linnaeus) was collected from nine districts in Selangor, Malaysia and tested with mosquito vaporizing mat bioassays. The same populations were also subjected to biochemical assays to investigate activities of detoxifying enzymes, namely non-specific esterase (EST), glutathione-S-transferase (GST) and mixed function oxidase (MFO). The efficacy of Ae. aegypti on the active ingredients tested in decreasing order were d- allethrin > dimefluthrin > prallethrin with PBO > prallethrin. The results further indicated significant enhancement mean levels of EST, GST and MFO in pyrethroid-resistant populations. The mortality rate of Ae. aegypti in response to pyrethroid active ingredients was associated with MFO activity, suggesting it is an important detoxification enzyme for the populations tested. In view of the presence of resistance against household insecticide products, pyrethroid efficacy on Ae. aegypti populations needs to be monitored closely to ensure the implementation of an effective vector control program in Malaysia. Malaysian Society of Parasitology and Tropical Medicine 2021 Article PeerReviewed Taib, Azratul Hizayu and Chen, Chee Dhang and Lau, K. W. and Abdul Wahid, Noor Azrizal and Tan, Tiong Kai and Lim, Yvonne Ai Lian and Azirun, Mohd Sofian and Low, Van Lun (2021) Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment. Tropical Biomedicine, 38 (3). 327 - 337. ISSN 0127-5720 https://msptm.org/vol-38-no-3-september/ 10.47665/tb.38.3.073
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description This study aims to examine the efficacy of mosquito mat vaporizers on Aedes aegypti and their associated metabolic detoxication mechanisms. For this purpose, Aedes aegypti (Linnaeus) was collected from nine districts in Selangor, Malaysia and tested with mosquito vaporizing mat bioassays. The same populations were also subjected to biochemical assays to investigate activities of detoxifying enzymes, namely non-specific esterase (EST), glutathione-S-transferase (GST) and mixed function oxidase (MFO). The efficacy of Ae. aegypti on the active ingredients tested in decreasing order were d- allethrin > dimefluthrin > prallethrin with PBO > prallethrin. The results further indicated significant enhancement mean levels of EST, GST and MFO in pyrethroid-resistant populations. The mortality rate of Ae. aegypti in response to pyrethroid active ingredients was associated with MFO activity, suggesting it is an important detoxification enzyme for the populations tested. In view of the presence of resistance against household insecticide products, pyrethroid efficacy on Ae. aegypti populations needs to be monitored closely to ensure the implementation of an effective vector control program in Malaysia.
format Article
author Taib, Azratul Hizayu
Chen, Chee Dhang
Lau, K. W.
Abdul Wahid, Noor Azrizal
Tan, Tiong Kai
Lim, Yvonne Ai Lian
Azirun, Mohd Sofian
Low, Van Lun
spellingShingle Taib, Azratul Hizayu
Chen, Chee Dhang
Lau, K. W.
Abdul Wahid, Noor Azrizal
Tan, Tiong Kai
Lim, Yvonne Ai Lian
Azirun, Mohd Sofian
Low, Van Lun
Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment
author_facet Taib, Azratul Hizayu
Chen, Chee Dhang
Lau, K. W.
Abdul Wahid, Noor Azrizal
Tan, Tiong Kai
Lim, Yvonne Ai Lian
Azirun, Mohd Sofian
Low, Van Lun
author_sort Taib, Azratul Hizayu
title Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment
title_short Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment
title_full Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment
title_fullStr Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment
title_full_unstemmed Bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in Aedes aegypti (Linnaeus) in Selangor, Malaysia: A statewide assessment
title_sort bioefficacy of mosquito mat vaporizers and associated metabolic detoxication mechanisms in aedes aegypti (linnaeus) in selangor, malaysia: a statewide assessment
publisher Malaysian Society of Parasitology and Tropical Medicine
publishDate 2021
url http://psasir.upm.edu.my/id/eprint/96224/
https://msptm.org/vol-38-no-3-september/
_version_ 1758579858274779136
score 13.211869

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