Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts

The 70% ethanolic extracts from eight neglected fruits; Muntingia calabura, Leucaena leucocephala, Spondias dulcis, Syzygium jambos, Mangifera caesia, Ardisia elliptica, Cynometra cauliflora and Ficus auriculata were evaluated for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, α...

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Main Authors: Mohamed Yunus, Siti Norhamimah, Abas, Faridah, Jaafar, Ahmad Haniff, Azizan, Awanis, Zolkeflee, Nur Khaleeda Zulaikha, Abd Ghafar, Siti Zulaikha
Format: Article
Published: Springer 2021
Online Access:http://psasir.upm.edu.my/id/eprint/95928/
https://link.springer.com/article/10.1007/s10068-020-00856-x
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spelling my.upm.eprints.959282023-03-21T04:58:32Z http://psasir.upm.edu.my/id/eprint/95928/ Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts Mohamed Yunus, Siti Norhamimah Abas, Faridah Jaafar, Ahmad Haniff Azizan, Awanis Zolkeflee, Nur Khaleeda Zulaikha Abd Ghafar, Siti Zulaikha The 70% ethanolic extracts from eight neglected fruits; Muntingia calabura, Leucaena leucocephala, Spondias dulcis, Syzygium jambos, Mangifera caesia, Ardisia elliptica, Cynometra cauliflora and Ficus auriculata were evaluated for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, α-glucosidase inhibitory activities as well as total phenolic content. The results of this study revealed that M. caesia fruit extract demonstrated the most potent radical scavenging activity. Among the fruits examined for α-glucosidase inhibitory activity, M. calabura and F. auriculata exhibited strong activity with no significant difference. The Pearson correlation indicated that the activities of M. caesia and F. auriculata contributed by phenolic compounds. A total of 65 metabolites were tentatively identified by using ultra-high-performance liquid chromatography tandem mass spectrometry (UHLPC-MS/MS). These findings suggested that the possible application of M. caesia and F. auriculata as a functional food with antioxidant and α-glucosidase inhibitory properties. Springer 2021 Article PeerReviewed Mohamed Yunus, Siti Norhamimah and Abas, Faridah and Jaafar, Ahmad Haniff and Azizan, Awanis and Zolkeflee, Nur Khaleeda Zulaikha and Abd Ghafar, Siti Zulaikha (2021) Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts. Food Science and Biotechnology, 30 (2). 195 - 208. ISSN 1226-7708; ESSN: 2092-6456 https://link.springer.com/article/10.1007/s10068-020-00856-x 10.1007/s10068-020-00856-x
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description The 70% ethanolic extracts from eight neglected fruits; Muntingia calabura, Leucaena leucocephala, Spondias dulcis, Syzygium jambos, Mangifera caesia, Ardisia elliptica, Cynometra cauliflora and Ficus auriculata were evaluated for their 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, α-glucosidase inhibitory activities as well as total phenolic content. The results of this study revealed that M. caesia fruit extract demonstrated the most potent radical scavenging activity. Among the fruits examined for α-glucosidase inhibitory activity, M. calabura and F. auriculata exhibited strong activity with no significant difference. The Pearson correlation indicated that the activities of M. caesia and F. auriculata contributed by phenolic compounds. A total of 65 metabolites were tentatively identified by using ultra-high-performance liquid chromatography tandem mass spectrometry (UHLPC-MS/MS). These findings suggested that the possible application of M. caesia and F. auriculata as a functional food with antioxidant and α-glucosidase inhibitory properties.
format Article
author Mohamed Yunus, Siti Norhamimah
Abas, Faridah
Jaafar, Ahmad Haniff
Azizan, Awanis
Zolkeflee, Nur Khaleeda Zulaikha
Abd Ghafar, Siti Zulaikha
spellingShingle Mohamed Yunus, Siti Norhamimah
Abas, Faridah
Jaafar, Ahmad Haniff
Azizan, Awanis
Zolkeflee, Nur Khaleeda Zulaikha
Abd Ghafar, Siti Zulaikha
Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts
author_facet Mohamed Yunus, Siti Norhamimah
Abas, Faridah
Jaafar, Ahmad Haniff
Azizan, Awanis
Zolkeflee, Nur Khaleeda Zulaikha
Abd Ghafar, Siti Zulaikha
author_sort Mohamed Yunus, Siti Norhamimah
title Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts
title_short Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts
title_full Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts
title_fullStr Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts
title_full_unstemmed Antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and UHPLC-MS/MS profile of the active extracts
title_sort antioxidant and α-glucosidase inhibitory activities of eight neglected fruit extracts and uhplc-ms/ms profile of the active extracts
publisher Springer
publishDate 2021
url http://psasir.upm.edu.my/id/eprint/95928/
https://link.springer.com/article/10.1007/s10068-020-00856-x
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