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An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications

Carboxylesterases (CEs) are members of prominent esterase, and as their name imply, they catalyze the cleavage of ester linkages. By far, a considerable number of novel CEs have been identified to investigate their exquisite physiological and biochemical properties. They are abundant enzymes in natu...

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Main Authors: Mohd Johan, Ummie Umaiera, Raja Abd Rahman, Raja Noor Zaliha, Kamarudin, Nor Hafizah Ahmad, Mohamad Ali, Mohd Shukuri
Format: Article
Published: Elsevier 2021
Online Access:http://psasir.upm.edu.my/id/eprint/95862/
https://www.sciencedirect.com/science/article/pii/S092777652100326X?via%3Dihub
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spelling my.upm.eprints.958622023-03-30T03:34:35Z http://psasir.upm.edu.my/id/eprint/95862/ An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications Mohd Johan, Ummie Umaiera Raja Abd Rahman, Raja Noor Zaliha Kamarudin, Nor Hafizah Ahmad Mohamad Ali, Mohd Shukuri Carboxylesterases (CEs) are members of prominent esterase, and as their name imply, they catalyze the cleavage of ester linkages. By far, a considerable number of novel CEs have been identified to investigate their exquisite physiological and biochemical properties. They are abundant enzymes in nature, widely distributed in relatively broad temperature range and in various sources; both macroorganisms and microorganisms. Given the importance of these enzymes in broad industries, interest in the study of their mechanisms and structural-based engineering are greatly increasing. This review presents the current state of knowledge and understanding about the structure and functions of this ester-metabolizing enzyme, primarily from bacterial sources. In addition, the potential biotechnological applications of bacterial CEs are also encompassed. This review will be useful in understanding the molecular basis and structural protein of bacterial CEs that are significant for the advancement of enzymology field in industries. Elsevier 2021 Article PeerReviewed Mohd Johan, Ummie Umaiera and Raja Abd Rahman, Raja Noor Zaliha and Kamarudin, Nor Hafizah Ahmad and Mohamad Ali, Mohd Shukuri (2021) An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications. Colloids and Surfaces B: Biointerfaces, 205. art. no. 111882. pp. 1-10. ISSN 0927-7765; ESSN: 1873-4367 https://www.sciencedirect.com/science/article/pii/S092777652100326X?via%3Dihub 10.1016/j.colsurfb.2021.111882
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description Carboxylesterases (CEs) are members of prominent esterase, and as their name imply, they catalyze the cleavage of ester linkages. By far, a considerable number of novel CEs have been identified to investigate their exquisite physiological and biochemical properties. They are abundant enzymes in nature, widely distributed in relatively broad temperature range and in various sources; both macroorganisms and microorganisms. Given the importance of these enzymes in broad industries, interest in the study of their mechanisms and structural-based engineering are greatly increasing. This review presents the current state of knowledge and understanding about the structure and functions of this ester-metabolizing enzyme, primarily from bacterial sources. In addition, the potential biotechnological applications of bacterial CEs are also encompassed. This review will be useful in understanding the molecular basis and structural protein of bacterial CEs that are significant for the advancement of enzymology field in industries.
format Article
author Mohd Johan, Ummie Umaiera
Raja Abd Rahman, Raja Noor Zaliha
Kamarudin, Nor Hafizah Ahmad
Mohamad Ali, Mohd Shukuri
spellingShingle Mohd Johan, Ummie Umaiera
Raja Abd Rahman, Raja Noor Zaliha
Kamarudin, Nor Hafizah Ahmad
Mohamad Ali, Mohd Shukuri
An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications
author_facet Mohd Johan, Ummie Umaiera
Raja Abd Rahman, Raja Noor Zaliha
Kamarudin, Nor Hafizah Ahmad
Mohamad Ali, Mohd Shukuri
author_sort Mohd Johan, Ummie Umaiera
title An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications
title_short An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications
title_full An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications
title_fullStr An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications
title_full_unstemmed An integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications
title_sort integrated overview of bacterial carboxylesterase: structure, function and biocatalytic applications
publisher Elsevier
publishDate 2021
url http://psasir.upm.edu.my/id/eprint/95862/
https://www.sciencedirect.com/science/article/pii/S092777652100326X?via%3Dihub
_version_ 1762394231845945344
score 13.211869

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