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Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review

Magnetic iron oxide nanoparticles (MIONs) with multifunctional properties have recently attracted significant attention from researchers, not only for their intrinsic scientific value, but also for the plethora of technological applications enabled by their wondrous properties. MIONs are defined by...

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Main Authors: Albert, Emmellie Laura, Norman, Ashreen, Mat Yaacob, Siti Nor Zulfikaini, Zainuri, Muhammad Zulfadzli, Che Abdullah, Che Azurahanim
Format: Article
Published: Electroactive Materials Society 2021
Online Access:http://psasir.upm.edu.my/id/eprint/95248/
https://www.electroactmater.com/index.php/volume-9-2021?id=60&subid=410
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spelling my.upm.eprints.952482023-02-02T09:04:16Z http://psasir.upm.edu.my/id/eprint/95248/ Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review Albert, Emmellie Laura Norman, Ashreen Mat Yaacob, Siti Nor Zulfikaini Zainuri, Muhammad Zulfadzli Che Abdullah, Che Azurahanim Magnetic iron oxide nanoparticles (MIONs) with multifunctional properties have recently attracted significant attention from researchers, not only for their intrinsic scientific value, but also for the plethora of technological applications enabled by their wondrous properties. MIONs are defined by their dipole configuration in the absence and presence of an external magnetic field, and their applications are diverse, including electronic, environmental, and biomedical. MIONs are well-known for their superparamagnetic properties, small size, and broad range of applications. MIONs have been found to be biocompatible with the human system to a degree since haemoglobin's chelator is composed of Fe (II) atoms. MIONs with desirable properties and a wide variety of biomedical applications are highly sought after. MIONs have received widespread recognition for their countless applications in a variety of fields, including nanobiotechnology and biomedicine. Due to their superparamagnetic properties and small size, MIONs are widely used in a variety of fields. Thus, this review highlights and describes the research related to biomedical applications based on MIONs synthesised using various approaches. This semi systematic mini review summarises the work that has been done thus far on MIONs, beginning with an overview of the various methods used to fabricate MIONs, including physical, chemical, and biological methods. Due to the importance of the surface chemistry of MIONs in biomedical applications, this review focuses on several common synthesis methods and their associated used in biomedical applications are defined. This review will assist new researchers in selecting appropriate MIONs synthesis techniques and for their research interests. MIONs are discussed as a vehicle for targeted drug delivery, as well as their use in cancer treatment via hyperthermia. Other biomedical applications discussed in detail include magnetic resonance imaging and magnetic targeting. Electroactive Materials Society 2021-08-26 Article PeerReviewed Albert, Emmellie Laura and Norman, Ashreen and Mat Yaacob, Siti Nor Zulfikaini and Zainuri, Muhammad Zulfadzli and Che Abdullah, Che Azurahanim (2021) Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review. International Journal of Electroactive Materials, 9 (2). 33 - 40. ISSN 2289-8360 https://www.electroactmater.com/index.php/volume-9-2021?id=60&subid=410
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description Magnetic iron oxide nanoparticles (MIONs) with multifunctional properties have recently attracted significant attention from researchers, not only for their intrinsic scientific value, but also for the plethora of technological applications enabled by their wondrous properties. MIONs are defined by their dipole configuration in the absence and presence of an external magnetic field, and their applications are diverse, including electronic, environmental, and biomedical. MIONs are well-known for their superparamagnetic properties, small size, and broad range of applications. MIONs have been found to be biocompatible with the human system to a degree since haemoglobin's chelator is composed of Fe (II) atoms. MIONs with desirable properties and a wide variety of biomedical applications are highly sought after. MIONs have received widespread recognition for their countless applications in a variety of fields, including nanobiotechnology and biomedicine. Due to their superparamagnetic properties and small size, MIONs are widely used in a variety of fields. Thus, this review highlights and describes the research related to biomedical applications based on MIONs synthesised using various approaches. This semi systematic mini review summarises the work that has been done thus far on MIONs, beginning with an overview of the various methods used to fabricate MIONs, including physical, chemical, and biological methods. Due to the importance of the surface chemistry of MIONs in biomedical applications, this review focuses on several common synthesis methods and their associated used in biomedical applications are defined. This review will assist new researchers in selecting appropriate MIONs synthesis techniques and for their research interests. MIONs are discussed as a vehicle for targeted drug delivery, as well as their use in cancer treatment via hyperthermia. Other biomedical applications discussed in detail include magnetic resonance imaging and magnetic targeting.
format Article
author Albert, Emmellie Laura
Norman, Ashreen
Mat Yaacob, Siti Nor Zulfikaini
Zainuri, Muhammad Zulfadzli
Che Abdullah, Che Azurahanim
spellingShingle Albert, Emmellie Laura
Norman, Ashreen
Mat Yaacob, Siti Nor Zulfikaini
Zainuri, Muhammad Zulfadzli
Che Abdullah, Che Azurahanim
Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review
author_facet Albert, Emmellie Laura
Norman, Ashreen
Mat Yaacob, Siti Nor Zulfikaini
Zainuri, Muhammad Zulfadzli
Che Abdullah, Che Azurahanim
author_sort Albert, Emmellie Laura
title Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review
title_short Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review
title_full Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review
title_fullStr Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review
title_full_unstemmed Synthesis and biomedical applications of magnetic iron oxide nanoparticles MIONs: a brief review
title_sort synthesis and biomedical applications of magnetic iron oxide nanoparticles mions: a brief review
publisher Electroactive Materials Society
publishDate 2021
url http://psasir.upm.edu.my/id/eprint/95248/
https://www.electroactmater.com/index.php/volume-9-2021?id=60&subid=410
_version_ 1758579845962399744
score 13.211869

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