Staff View: Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest

Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest

Picrasma javanica Blume is a plant belonging to Simaroubaceae. It is known for its secondary metabolites, namely quassinoids, offering various pharmacological properties including antitumor, antimalarial, and antiviral. The plant is traditionally used as a source medicine for different diseases in M...

Full description

Saved in:

Bibliographic Details
Main Authors:	Bakhtiar, Muhammad Taher, Mohd Razali, Najah Fatehah, Darnis, Deny Susanti, Rahman, Md. Atiar, Artasasta, Muh Ade, Zakaria, Zainul Amiruddin
Format:	Article
Published:	Penerbit Universiti Kebangsaan Malaysia 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/94604/ http://www.ukm.my/jsm/english_journals/vol51num3_2022/contentsVol51num3_2022.html
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.upm.eprints.94604
record_format	eprints
spelling	my.upm.eprints.946042022-12-07T01:15:55Z http://psasir.upm.edu.my/id/eprint/94604/ Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest Bakhtiar, Muhammad Taher Mohd Razali, Najah Fatehah Darnis, Deny Susanti Rahman, Md. Atiar Artasasta, Muh Ade Zakaria, Zainul Amiruddin Picrasma javanica Blume is a plant belonging to Simaroubaceae. It is known for its secondary metabolites, namely quassinoids, offering various pharmacological properties including antitumor, antimalarial, and antiviral. The plant is traditionally used as a source medicine for different diseases in Myanmar, Thailand, and Indonesia. Despite the extensive studies on P. javanica, there is no concise and conclusive information regarding the phytochemical and phytochemistry of the plant has been reported. Thus, we aimed to discern the phytochemical constituents and pharmacological activities of P. javanica. The phytochemical constituents and pharmacological benefits of P. javanica were reviewed and supported from previous in vivo and in vitro studies. The literature used in this review were retrieved from electronic database such as Scopus, Semanticscholar, Sciendirect, Google scholar, Researchgate, Pubmed, and websites. P. javanica possesses several phytochemical constituents, such as quassinoids, alkaloids, and triterpenoids. The compounds of the plant have been isolated and studied for their pharmacological activities, encompassing antimalarial, antiproliferative, antiviral, antimicrobial, and membrane-stabilizing activities. It was found that the pharmacological activities in the plant were attributable to the key ingredients of quassinoids and alkaloids present. However, further extensive studies must be carried out to explore more potential benefits that the plant could offer. Penerbit Universiti Kebangsaan Malaysia 2022-03 Article PeerReviewed Bakhtiar, Muhammad Taher and Mohd Razali, Najah Fatehah and Darnis, Deny Susanti and Rahman, Md. Atiar and Artasasta, Muh Ade and Zakaria, Zainul Amiruddin (2022) Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest. Sains Malaysiana, 51 (3). pp. 757-774. ISSN 0126-6039; ESSN: 2735-0118 http://www.ukm.my/jsm/english_journals/vol51num3_2022/contentsVol51num3_2022.html 10.17576/jsm-2022-5103-10
institution	Universiti Putra Malaysia
building	UPM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Putra Malaysia
content_source	UPM Institutional Repository
url_provider	http://psasir.upm.edu.my/
description	Picrasma javanica Blume is a plant belonging to Simaroubaceae. It is known for its secondary metabolites, namely quassinoids, offering various pharmacological properties including antitumor, antimalarial, and antiviral. The plant is traditionally used as a source medicine for different diseases in Myanmar, Thailand, and Indonesia. Despite the extensive studies on P. javanica, there is no concise and conclusive information regarding the phytochemical and phytochemistry of the plant has been reported. Thus, we aimed to discern the phytochemical constituents and pharmacological activities of P. javanica. The phytochemical constituents and pharmacological benefits of P. javanica were reviewed and supported from previous in vivo and in vitro studies. The literature used in this review were retrieved from electronic database such as Scopus, Semanticscholar, Sciendirect, Google scholar, Researchgate, Pubmed, and websites. P. javanica possesses several phytochemical constituents, such as quassinoids, alkaloids, and triterpenoids. The compounds of the plant have been isolated and studied for their pharmacological activities, encompassing antimalarial, antiproliferative, antiviral, antimicrobial, and membrane-stabilizing activities. It was found that the pharmacological activities in the plant were attributable to the key ingredients of quassinoids and alkaloids present. However, further extensive studies must be carried out to explore more potential benefits that the plant could offer.
format	Article
author	Bakhtiar, Muhammad Taher Mohd Razali, Najah Fatehah Darnis, Deny Susanti Rahman, Md. Atiar Artasasta, Muh Ade Zakaria, Zainul Amiruddin
spellingShingle	Bakhtiar, Muhammad Taher Mohd Razali, Najah Fatehah Darnis, Deny Susanti Rahman, Md. Atiar Artasasta, Muh Ade Zakaria, Zainul Amiruddin Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest
author_facet	Bakhtiar, Muhammad Taher Mohd Razali, Najah Fatehah Darnis, Deny Susanti Rahman, Md. Atiar Artasasta, Muh Ade Zakaria, Zainul Amiruddin
author_sort	Bakhtiar, Muhammad Taher
title	Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest
title_short	Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest
title_full	Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest
title_fullStr	Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest
title_full_unstemmed	Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest
title_sort	phytochemical constituents and pharmacological activities of picrasma javanica: quassinoids interest
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2022
url	http://psasir.upm.edu.my/id/eprint/94604/ http://www.ukm.my/jsm/english_journals/vol51num3_2022/contentsVol51num3_2022.html
_version_	1753789930735140864
score	13.211869

Phytochemical constituents and pharmacological activities of Picrasma javanica: quassinoids interest

Similar Items