Mitragynine (Kratom)-induced cognitive impairments in mice resemble Δ9-THC and morphine effects: reversal by cannabinoid CB1 receptor antagonism
Kratom is a widely abused plant-based drug preparation with a global interest in recent years, well beyond its native grounds in Southeast Asia. Mitragynine, its major psychoactive constituent is known to exhibit opioid-like behavioral effects with resultant neuroplasticity in the brain reward syste...
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Main Authors: | Ismail, Nurul Iman, Ahmad, Nur Aimi Zawami, Mohd Yusof, Nurul Aiman, Talib, Ummi Nasrah, Norazit, Anwar, Kumar, Jaya, Mehat, Muhammad Zulfadli, Hassan, Zurina, Muller, Christian P., Muzaimi, Mustapha |
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Format: | Article |
Published: |
Frontiers Media
2021
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Online Access: | http://psasir.upm.edu.my/id/eprint/94208/ https://www.frontiersin.org/articles/10.3389/fphar.2021.708055/full |
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