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Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system

This study aims to evaluate the influence of Vitamin A and E homologues toward acrylamide in equimolar asparagine-glucose model system. Vitamin A homologue as β-carotene (BC) and five Vitamin E homologues, i.e., α-tocopherol (AT), δ-tocopherol (DT), α-tocotrienol (ATT), γ-tocotrienol (GTT), and δ-to...

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Main Authors: Kuek, Su Lee, Ahmad Tarmizi, Azmil Haizam, Abd Razak, Raznim Arni, Jinap, Selamat, Sanny, Maimunah
Format: Article
Published: MDPI 2021
Online Access:http://psasir.upm.edu.my/id/eprint/93556/
https://www.mdpi.com/journal/antioxidants
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spelling my.upm.eprints.935562023-10-23T07:11:39Z http://psasir.upm.edu.my/id/eprint/93556/ Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system Kuek, Su Lee Ahmad Tarmizi, Azmil Haizam Abd Razak, Raznim Arni Jinap, Selamat Sanny, Maimunah This study aims to evaluate the influence of Vitamin A and E homologues toward acrylamide in equimolar asparagine-glucose model system. Vitamin A homologue as β-carotene (BC) and five Vitamin E homologues, i.e., α-tocopherol (AT), δ-tocopherol (DT), α-tocotrienol (ATT), γ-tocotrienol (GTT), and δ-tocotrienol (DTT), were tested at different concentrations (1 and 10 µmol) and subjected to heating at 160 °C for 20 min before acrylamide quantification. At lower concentrations (1 µmol; 431, 403, 411 ppm, respectively), AT, DT, and GTT significantly increase acrylamide. Except for DT, enhancing concentration to 10 µmol (5370, 4310, 4250, 3970, and 4110 ppm, respectively) caused significant acrylamide formation. From linear regression model, acrylamide concentration demonstrated significant depreciation over concentration increase in AT (Beta = −83.0, R2 = 0.652, p ≤ 0.05) and DT (Beta = −71.6, R2 = 0.930, p ≤ 0.05). This study indicates that different Vitamin A and E homologue concentrations could determine their functionality either as antioxidants or pro-oxidants. MDPI 2021-06-22 Article PeerReviewed Kuek, Su Lee and Ahmad Tarmizi, Azmil Haizam and Abd Razak, Raznim Arni and Jinap, Selamat and Sanny, Maimunah (2021) Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system. Antioxidants, 10 (7). art. no. 993. pp. 1-10. ISSN 2076-3921 https://www.mdpi.com/journal/antioxidants 10.3390/antiox10070993
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description This study aims to evaluate the influence of Vitamin A and E homologues toward acrylamide in equimolar asparagine-glucose model system. Vitamin A homologue as β-carotene (BC) and five Vitamin E homologues, i.e., α-tocopherol (AT), δ-tocopherol (DT), α-tocotrienol (ATT), γ-tocotrienol (GTT), and δ-tocotrienol (DTT), were tested at different concentrations (1 and 10 µmol) and subjected to heating at 160 °C for 20 min before acrylamide quantification. At lower concentrations (1 µmol; 431, 403, 411 ppm, respectively), AT, DT, and GTT significantly increase acrylamide. Except for DT, enhancing concentration to 10 µmol (5370, 4310, 4250, 3970, and 4110 ppm, respectively) caused significant acrylamide formation. From linear regression model, acrylamide concentration demonstrated significant depreciation over concentration increase in AT (Beta = −83.0, R2 = 0.652, p ≤ 0.05) and DT (Beta = −71.6, R2 = 0.930, p ≤ 0.05). This study indicates that different Vitamin A and E homologue concentrations could determine their functionality either as antioxidants or pro-oxidants.
format Article
author Kuek, Su Lee
Ahmad Tarmizi, Azmil Haizam
Abd Razak, Raznim Arni
Jinap, Selamat
Sanny, Maimunah
spellingShingle Kuek, Su Lee
Ahmad Tarmizi, Azmil Haizam
Abd Razak, Raznim Arni
Jinap, Selamat
Sanny, Maimunah
Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system
author_facet Kuek, Su Lee
Ahmad Tarmizi, Azmil Haizam
Abd Razak, Raznim Arni
Jinap, Selamat
Sanny, Maimunah
author_sort Kuek, Su Lee
title Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system
title_short Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system
title_full Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system
title_fullStr Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system
title_full_unstemmed Vitamin A and E homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system
title_sort vitamin a and e homologues impacting the fate of acrylamide in equimolar asparagine-glucose model system
publisher MDPI
publishDate 2021
url http://psasir.upm.edu.my/id/eprint/93556/
https://www.mdpi.com/journal/antioxidants
_version_ 1781706670873772032
score 13.211869

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