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Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain

Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis. A combination of clinical, radiological, biochemical, and pathological findings is needed for accurate diagnosis. Case report: Herein, we present...

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Main Authors: Md Noh, Mohamad Syafeeq Faeez, Rajadurai, Naveen, Hassan, Thajunnisa, Alias, Mardziah, Robert, Penafort, Chong, Yip Boon
Format: Article
Published: Elsevier 2021
Online Access:http://psasir.upm.edu.my/id/eprint/93544/
https://www.sciencedirect.com/science/article/pii/S2214751921002425
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spelling my.upm.eprints.935442023-01-13T03:34:38Z http://psasir.upm.edu.my/id/eprint/93544/ Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain Md Noh, Mohamad Syafeeq Faeez Rajadurai, Naveen Hassan, Thajunnisa Alias, Mardziah Robert, Penafort Chong, Yip Boon Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis. A combination of clinical, radiological, biochemical, and pathological findings is needed for accurate diagnosis. Case report: Herein, we present a young male presenting with acute back pain, initially suspicious of malignancy, with an eventual diagnosis of vertebral sarcoidosis; with sacrum, pelvic bone, and cutaneous involvement (Darier-Roussy disease), as well as associated mediastinal and abdominal lymphadenopathy. Following the diagnosis of vertebral sarcoidosis with associated Darier-Roussy disease, the patient was offered treatment but was not keen at the time of diagnosis. An outpatient appointment to re-discuss treatment options was given, should it be pursued. Conclusion: Vertebral sarcoidosis with associated Darier-Roussy disease is an extremely rare clinical entity, with multiple differential diagnoses. Pathological examination is confirmatory and should be pursued for accurate diagnosis and treatment. Elsevier 2021-12 Article PeerReviewed Md Noh, Mohamad Syafeeq Faeez and Rajadurai, Naveen and Hassan, Thajunnisa and Alias, Mardziah and Robert, Penafort and Chong, Yip Boon (2021) Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain. Interdisciplinary Neurosurgery: Advanced Techniques and Case Management, 26. art. no. 101330. pp. 1-6. ISSN 2214-7519 https://www.sciencedirect.com/science/article/pii/S2214751921002425 10.1016/j.inat.2021.101330
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description Introduction: Sarcoidosis is a systemic granulomatous disease of unknown etiology, with a heterogenous clinical manifestation, progression, and prognosis. A combination of clinical, radiological, biochemical, and pathological findings is needed for accurate diagnosis. Case report: Herein, we present a young male presenting with acute back pain, initially suspicious of malignancy, with an eventual diagnosis of vertebral sarcoidosis; with sacrum, pelvic bone, and cutaneous involvement (Darier-Roussy disease), as well as associated mediastinal and abdominal lymphadenopathy. Following the diagnosis of vertebral sarcoidosis with associated Darier-Roussy disease, the patient was offered treatment but was not keen at the time of diagnosis. An outpatient appointment to re-discuss treatment options was given, should it be pursued. Conclusion: Vertebral sarcoidosis with associated Darier-Roussy disease is an extremely rare clinical entity, with multiple differential diagnoses. Pathological examination is confirmatory and should be pursued for accurate diagnosis and treatment.
format Article
author Md Noh, Mohamad Syafeeq Faeez
Rajadurai, Naveen
Hassan, Thajunnisa
Alias, Mardziah
Robert, Penafort
Chong, Yip Boon
spellingShingle Md Noh, Mohamad Syafeeq Faeez
Rajadurai, Naveen
Hassan, Thajunnisa
Alias, Mardziah
Robert, Penafort
Chong, Yip Boon
Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
author_facet Md Noh, Mohamad Syafeeq Faeez
Rajadurai, Naveen
Hassan, Thajunnisa
Alias, Mardziah
Robert, Penafort
Chong, Yip Boon
author_sort Md Noh, Mohamad Syafeeq Faeez
title Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
title_short Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
title_full Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
title_fullStr Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
title_full_unstemmed Vertebral sarcoidosis with associated Darier-Roussy disease manifesting as acute back pain
title_sort vertebral sarcoidosis with associated darier-roussy disease manifesting as acute back pain
publisher Elsevier
publishDate 2021
url http://psasir.upm.edu.my/id/eprint/93544/
https://www.sciencedirect.com/science/article/pii/S2214751921002425
_version_ 1755873903771648000
score 13.211869

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