Transplanted erythropoietin-expressing mesenchymal stem cells promote pro-survival gene expression and protect photoreceptors from sodium iodate-induced cytotoxicity in a retinal degeneration model
Mesenchymal stem cells (MSC) are highly regarded as a potential treatment for retinal degenerative disorders like retinitis pigmentosa and age-related macular degeneration. However, donor cell heterogeneity and inconsistent protocols for transplantation have led to varied outcomes in clinical trials...
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Main Authors: | Koh, Avin Ee Hwan, Alsaeedi, Hiba Amer, Abd Rashid, Munirah, Lam, Chenshen, Harun, Mohd Hairul Nizam, Ng, Min Hwei, Mohd Isa, Hazlita, Then, Kong Yong, Mae-Lynn, Catherine Bastion, Aisha Farhana, Alam, Mohammad Khursheed, Subbiah, Suresh Kumar, Mok, Pooi Ling |
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Format: | Article |
Language: | English |
Published: |
Frontiers
2021
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Online Access: | http://psasir.upm.edu.my/id/eprint/93428/1/Transplanted%20erythropoietin-expressing.pdf http://psasir.upm.edu.my/id/eprint/93428/ https://www.frontiersin.org/articles/10.3389/fcell.2021.764504/full |
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