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Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk

Introduction: Consumption of Chinese Herbal Medicine (CHMs) have escalated globally. They are preferred treatment for minor diseases or disorders. In Malaysia, CHMs are common home remedies during pregnancy and postpartum. Angelica sinensis (Danggui) is a staple CHMs during postpartum for purpose of...

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Main Authors: Ahmad Bustami, Normina, Ho, Yu Bin, Tan, Chung Keat, Aris, Ahmad Zaharin, Tan, Eugenie Sin Sing
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2020
Online Access:http://psasir.upm.edu.my/id/eprint/90230/1/18upm.pdf
http://psasir.upm.edu.my/id/eprint/90230/
https://medic.upm.edu.my/upload/dokumen/2020090810211318_MJMHS_0427.pdf
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spelling my.upm.eprints.902302021-09-09T21:53:28Z http://psasir.upm.edu.my/id/eprint/90230/ Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk Ahmad Bustami, Normina Ho, Yu Bin Tan, Chung Keat Aris, Ahmad Zaharin Tan, Eugenie Sin Sing Introduction: Consumption of Chinese Herbal Medicine (CHMs) have escalated globally. They are preferred treatment for minor diseases or disorders. In Malaysia, CHMs are common home remedies during pregnancy and postpartum. Angelica sinensis (Danggui) is a staple CHMs during postpartum for purpose of nourishing blood and resolving stasis. Concerns are raised over possible heavy metals toxicity. Objective: This study aims to (i) determine Danggui consumption among postpartum mothers, (ii) quantify its heavy metals level, namely Lead (Pb), Cadmium (Cd), Arsenic (As) and Chromium (Cr) and (iii) determine health risks of Danggui consumption among mothers. Methods: A cross-sectional study involving 112 postpartum mothers was carried out in Kuala Lumpur. Danggui samples were collected from nine districts in Kuala Lumpur (Segambut, Seputeh, Cheras, Kepong, Bandar Tun Razak, Titiwangsa, Setiawangsa, Batu and Lembah Pantai). Heavy metals were extracted using microwave digester and analysed using Inductively coupled plasma mass spectrometry (ICPMS). Hazard Quotient (HQ) was used to determine non-carcinogenic health risks for herbal medicine consumption. Results: Danggui was consumed by 19.6% of mothers (n=22). Among them, incidence of jaundice was 63.6% and need for phototherapy was 40.9%. Heavy metals contaminations were found in the decreasing order of Cr > As > Pb > Cd with median (interquartile) of 3996.3 (2805.6) μg/ kg, 128.3 (56.7), 98.6 (99.1) and 37.0 (35.0) respectively. No non-carcinogenic health risks were found for all four metals. Conclusion: Alarming concentrations of heavy metals were quantified in Danggui warranting for further investigation to safeguard health of postpartum mothers. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2020-09 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/90230/1/18upm.pdf Ahmad Bustami, Normina and Ho, Yu Bin and Tan, Chung Keat and Aris, Ahmad Zaharin and Tan, Eugenie Sin Sing (2020) Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk. Malaysian Journal of Medicine and Health Sciences, 16 (3). pp. 113-117. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2020090810211318_MJMHS_0427.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Introduction: Consumption of Chinese Herbal Medicine (CHMs) have escalated globally. They are preferred treatment for minor diseases or disorders. In Malaysia, CHMs are common home remedies during pregnancy and postpartum. Angelica sinensis (Danggui) is a staple CHMs during postpartum for purpose of nourishing blood and resolving stasis. Concerns are raised over possible heavy metals toxicity. Objective: This study aims to (i) determine Danggui consumption among postpartum mothers, (ii) quantify its heavy metals level, namely Lead (Pb), Cadmium (Cd), Arsenic (As) and Chromium (Cr) and (iii) determine health risks of Danggui consumption among mothers. Methods: A cross-sectional study involving 112 postpartum mothers was carried out in Kuala Lumpur. Danggui samples were collected from nine districts in Kuala Lumpur (Segambut, Seputeh, Cheras, Kepong, Bandar Tun Razak, Titiwangsa, Setiawangsa, Batu and Lembah Pantai). Heavy metals were extracted using microwave digester and analysed using Inductively coupled plasma mass spectrometry (ICPMS). Hazard Quotient (HQ) was used to determine non-carcinogenic health risks for herbal medicine consumption. Results: Danggui was consumed by 19.6% of mothers (n=22). Among them, incidence of jaundice was 63.6% and need for phototherapy was 40.9%. Heavy metals contaminations were found in the decreasing order of Cr > As > Pb > Cd with median (interquartile) of 3996.3 (2805.6) μg/ kg, 128.3 (56.7), 98.6 (99.1) and 37.0 (35.0) respectively. No non-carcinogenic health risks were found for all four metals. Conclusion: Alarming concentrations of heavy metals were quantified in Danggui warranting for further investigation to safeguard health of postpartum mothers.
format Article
author Ahmad Bustami, Normina
Ho, Yu Bin
Tan, Chung Keat
Aris, Ahmad Zaharin
Tan, Eugenie Sin Sing
spellingShingle Ahmad Bustami, Normina
Ho, Yu Bin
Tan, Chung Keat
Aris, Ahmad Zaharin
Tan, Eugenie Sin Sing
Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk
author_facet Ahmad Bustami, Normina
Ho, Yu Bin
Tan, Chung Keat
Aris, Ahmad Zaharin
Tan, Eugenie Sin Sing
author_sort Ahmad Bustami, Normina
title Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk
title_short Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk
title_full Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk
title_fullStr Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk
title_full_unstemmed Heavy metals in Danggui (Angelica sinensis) consumed by postpartum mothers and its health risk
title_sort heavy metals in danggui (angelica sinensis) consumed by postpartum mothers and its health risk
publisher Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
publishDate 2020
url http://psasir.upm.edu.my/id/eprint/90230/1/18upm.pdf
http://psasir.upm.edu.my/id/eprint/90230/
https://medic.upm.edu.my/upload/dokumen/2020090810211318_MJMHS_0427.pdf
_version_ 1712286768235020288
score 13.211869

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