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Isolated renal sarcoidosis with acute kidney injury - a rare entity

Sarcoidosis is a multisystem inflammatory disorder that commonly affecting the lungs. However, isolated renal sarcoidosis without lung involvement is a rare condition. Sarcoidosis is known to cause kidney involvement via different mechanisms. Hypercalcemia and hypercalciuria may trigger renal stones...

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Main Authors: Ng, Tze Jian, Thiam, Christopher Seong Lim, Omar, Noorjehan, Abd Ghani, Fauzah, Goh, Bak Leong
Format: Article
Language:English
Published: Malaysian Society of Nephrology 2020
Online Access:http://psasir.upm.edu.my/id/eprint/89477/1/RENAL.pdf
http://psasir.upm.edu.my/id/eprint/89477/
https://www.jctn.msn.org.my/index.php/ejournal/article/view/45
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spelling my.upm.eprints.894772021-09-20T08:23:40Z http://psasir.upm.edu.my/id/eprint/89477/ Isolated renal sarcoidosis with acute kidney injury - a rare entity Ng, Tze Jian Thiam, Christopher Seong Lim Omar, Noorjehan Abd Ghani, Fauzah Goh, Bak Leong Sarcoidosis is a multisystem inflammatory disorder that commonly affecting the lungs. However, isolated renal sarcoidosis without lung involvement is a rare condition. Sarcoidosis is known to cause kidney involvement via different mechanisms. Hypercalcemia and hypercalciuria may trigger renal stones formation and result in obstructive uropathy. Sarcoidosis can also cause interstitial nephritis with or without granuloma formation in the kidneys. The true incidence of renal involvement in sarcoidosis is unknown as renal biopsy is not routinely performed unless there is presence of renal impairment. Renal sarcoidosis is a diagnosis of exclusion supported by the typical histopathological findings. Due to the scarcity of this disease, there is no universal guideline or recommendation regarding the diagnosis and treatment for renal sarcoidosis. Here we present a case that initially presented to us with rapid deterioration of kidney function, which was later proven to be renal sarcoidosis, followed by a literature review. Malaysian Society of Nephrology 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/89477/1/RENAL.pdf Ng, Tze Jian and Thiam, Christopher Seong Lim and Omar, Noorjehan and Abd Ghani, Fauzah and Goh, Bak Leong (2020) Isolated renal sarcoidosis with acute kidney injury - a rare entity. Journal of Clinical and Translational Nephrology, 2. art. no. 3. pp. 1-6. ISSN 2710-5903 https://www.jctn.msn.org.my/index.php/ejournal/article/view/45
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Sarcoidosis is a multisystem inflammatory disorder that commonly affecting the lungs. However, isolated renal sarcoidosis without lung involvement is a rare condition. Sarcoidosis is known to cause kidney involvement via different mechanisms. Hypercalcemia and hypercalciuria may trigger renal stones formation and result in obstructive uropathy. Sarcoidosis can also cause interstitial nephritis with or without granuloma formation in the kidneys. The true incidence of renal involvement in sarcoidosis is unknown as renal biopsy is not routinely performed unless there is presence of renal impairment. Renal sarcoidosis is a diagnosis of exclusion supported by the typical histopathological findings. Due to the scarcity of this disease, there is no universal guideline or recommendation regarding the diagnosis and treatment for renal sarcoidosis. Here we present a case that initially presented to us with rapid deterioration of kidney function, which was later proven to be renal sarcoidosis, followed by a literature review.
format Article
author Ng, Tze Jian
Thiam, Christopher Seong Lim
Omar, Noorjehan
Abd Ghani, Fauzah
Goh, Bak Leong
spellingShingle Ng, Tze Jian
Thiam, Christopher Seong Lim
Omar, Noorjehan
Abd Ghani, Fauzah
Goh, Bak Leong
Isolated renal sarcoidosis with acute kidney injury - a rare entity
author_facet Ng, Tze Jian
Thiam, Christopher Seong Lim
Omar, Noorjehan
Abd Ghani, Fauzah
Goh, Bak Leong
author_sort Ng, Tze Jian
title Isolated renal sarcoidosis with acute kidney injury - a rare entity
title_short Isolated renal sarcoidosis with acute kidney injury - a rare entity
title_full Isolated renal sarcoidosis with acute kidney injury - a rare entity
title_fullStr Isolated renal sarcoidosis with acute kidney injury - a rare entity
title_full_unstemmed Isolated renal sarcoidosis with acute kidney injury - a rare entity
title_sort isolated renal sarcoidosis with acute kidney injury - a rare entity
publisher Malaysian Society of Nephrology
publishDate 2020
url http://psasir.upm.edu.my/id/eprint/89477/1/RENAL.pdf
http://psasir.upm.edu.my/id/eprint/89477/
https://www.jctn.msn.org.my/index.php/ejournal/article/view/45
_version_ 1712286764800933888
score 13.211869

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