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Herbal medication triggering lupus nephritis - a case report

Background: Herbal medication is widely used in our region as a mode of alternative medicine. Its contents and combinations are often modified to suit the needs of different populations. These products are said to boost the immune system and may serve as a protective measure against many diseases in...

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Main Authors: Abdul Rashid, Anna Misya’il, Abd Ghani, Fauzah, Inche Mat, Liyana Najwa, Thiam, Christopher Seong Lim
Format: Article
Language:English
Published: BioMed Central 2020
Online Access:http://psasir.upm.edu.my/id/eprint/89171/1/LUPUS.pdf
http://psasir.upm.edu.my/id/eprint/89171/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268707
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spelling my.upm.eprints.891712021-09-03T22:21:14Z http://psasir.upm.edu.my/id/eprint/89171/ Herbal medication triggering lupus nephritis - a case report Abdul Rashid, Anna Misya’il Abd Ghani, Fauzah Inche Mat, Liyana Najwa Thiam, Christopher Seong Lim Background: Herbal medication is widely used in our region as a mode of alternative medicine. Its contents and combinations are often modified to suit the needs of different populations. These products are said to boost the immune system and may serve as a protective measure against many diseases including Systemic Lupus Erythematosus (SLE). Some even lay claims to be able to cure SLE. Although they are not without side effects, these medications are still preferred due to their widespread availability and affordability, compared to modern medications. However, to date, there have been no reported cases in which these traditional medications can trigger a lupus-like reaction, moreover one involving the kidneys. Case presentation: We report a patient who developed overt lupus nephritis after consuming a course of herbal supplement. Her renal status did not improve upon cessation of the offending drug, and she required immunosuppressive therapy. After one cycle of IV cyclophosphamide, we managed to get the patient into remission - she is now on tapering doses of steroids. Conclusion: We wish to highlight the possibility of consumption of herbal medication and the emergence of drug-induced lupus nephritis. A thorough anamnesis and high index of suspicion of drug-induced lupus nephritis is warranted when a patient on supplements presents with urinary abnormalities. BioMed Central 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/89171/1/LUPUS.pdf Abdul Rashid, Anna Misya’il and Abd Ghani, Fauzah and Inche Mat, Liyana Najwa and Thiam, Christopher Seong Lim (2020) Herbal medication triggering lupus nephritis - a case report. BMC Complementary Medicine and Therapies, 20 (1). art. no. 163. pp. 1-6. ISSN 2662-7671 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268707 10.1186/s12906-020-02971-y
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Background: Herbal medication is widely used in our region as a mode of alternative medicine. Its contents and combinations are often modified to suit the needs of different populations. These products are said to boost the immune system and may serve as a protective measure against many diseases including Systemic Lupus Erythematosus (SLE). Some even lay claims to be able to cure SLE. Although they are not without side effects, these medications are still preferred due to their widespread availability and affordability, compared to modern medications. However, to date, there have been no reported cases in which these traditional medications can trigger a lupus-like reaction, moreover one involving the kidneys. Case presentation: We report a patient who developed overt lupus nephritis after consuming a course of herbal supplement. Her renal status did not improve upon cessation of the offending drug, and she required immunosuppressive therapy. After one cycle of IV cyclophosphamide, we managed to get the patient into remission - she is now on tapering doses of steroids. Conclusion: We wish to highlight the possibility of consumption of herbal medication and the emergence of drug-induced lupus nephritis. A thorough anamnesis and high index of suspicion of drug-induced lupus nephritis is warranted when a patient on supplements presents with urinary abnormalities.
format Article
author Abdul Rashid, Anna Misya’il
Abd Ghani, Fauzah
Inche Mat, Liyana Najwa
Thiam, Christopher Seong Lim
spellingShingle Abdul Rashid, Anna Misya’il
Abd Ghani, Fauzah
Inche Mat, Liyana Najwa
Thiam, Christopher Seong Lim
Herbal medication triggering lupus nephritis - a case report
author_facet Abdul Rashid, Anna Misya’il
Abd Ghani, Fauzah
Inche Mat, Liyana Najwa
Thiam, Christopher Seong Lim
author_sort Abdul Rashid, Anna Misya’il
title Herbal medication triggering lupus nephritis - a case report
title_short Herbal medication triggering lupus nephritis - a case report
title_full Herbal medication triggering lupus nephritis - a case report
title_fullStr Herbal medication triggering lupus nephritis - a case report
title_full_unstemmed Herbal medication triggering lupus nephritis - a case report
title_sort herbal medication triggering lupus nephritis - a case report
publisher BioMed Central
publishDate 2020
url http://psasir.upm.edu.my/id/eprint/89171/1/LUPUS.pdf
http://psasir.upm.edu.my/id/eprint/89171/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268707
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score 13.211869

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