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Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology

Eleutherine bulbosa Mill. bulb or Dayak onion was reported to have various health benefits. However, the study of the phenolic content and antioxidant activity of this plant is scarce. This work was aimed to optimise the extraction of phenolic compounds from E. bulbosa bulb using response surface me...

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Main Authors: Kamarudin, Ammar Akram, Mohd. Esa, Norhaizan, Saad, Norazalina, Sayuti, Nor Hafiza, Ab. Razak, Nor asma
Format: Article
Language:English
Published: Elsevier 2020
Online Access:http://psasir.upm.edu.my/id/eprint/89163/1/BULB.pdf
http://psasir.upm.edu.my/id/eprint/89163/
https://www.sciencedirect.com/science/article/pii/S092666901931074X
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spelling my.upm.eprints.891632021-09-20T23:52:53Z http://psasir.upm.edu.my/id/eprint/89163/ Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology Kamarudin, Ammar Akram Mohd. Esa, Norhaizan Saad, Norazalina Sayuti, Nor Hafiza Ab. Razak, Nor asma Eleutherine bulbosa Mill. bulb or Dayak onion was reported to have various health benefits. However, the study of the phenolic content and antioxidant activity of this plant is scarce. This work was aimed to optimise the extraction of phenolic compounds from E. bulbosa bulb using response surface methodology (RSM). The antioxidant activities of the extracts were then analysed. Central Composite Design (CCD) was employed with four factors at five coded levels. The extraction parameters employed were temperature (), extraction time (), solid-liquid ratio (), and ethanol concentration (), which were found to affect response variables significantly; thus, fitted the second-order polynomial. The optimum extraction conditions obtained were temperature (): 45 °C, extraction time (): 70 min, solid-liquid ratio (): 10:146 (w/v), and ethanol concentration (): 90 %. HPLC analysis revealed eight biologically active constituents such as eleutherine, gallic acid, chlorogenic acid, quercetin, kaempferol, rutin, epicatechin gallate, and myricetin. The findings suggested the potential application of a useful, clean, cost-effective method of RSM to acquire these biologically active compounds from E. bulbosa bulb that could be utilised in food applications and future pharmaceutical industries. Elsevier 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/89163/1/BULB.pdf Kamarudin, Ammar Akram and Mohd. Esa, Norhaizan and Saad, Norazalina and Sayuti, Nor Hafiza and Ab. Razak, Nor asma (2020) Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology. Industrial Crops and Products, 144. art. no. 112064. pp. 1-8. ISSN 0926-6690 https://www.sciencedirect.com/science/article/pii/S092666901931074X 10.1016/j.indcrop.2019.112064
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Eleutherine bulbosa Mill. bulb or Dayak onion was reported to have various health benefits. However, the study of the phenolic content and antioxidant activity of this plant is scarce. This work was aimed to optimise the extraction of phenolic compounds from E. bulbosa bulb using response surface methodology (RSM). The antioxidant activities of the extracts were then analysed. Central Composite Design (CCD) was employed with four factors at five coded levels. The extraction parameters employed were temperature (), extraction time (), solid-liquid ratio (), and ethanol concentration (), which were found to affect response variables significantly; thus, fitted the second-order polynomial. The optimum extraction conditions obtained were temperature (): 45 °C, extraction time (): 70 min, solid-liquid ratio (): 10:146 (w/v), and ethanol concentration (): 90 %. HPLC analysis revealed eight biologically active constituents such as eleutherine, gallic acid, chlorogenic acid, quercetin, kaempferol, rutin, epicatechin gallate, and myricetin. The findings suggested the potential application of a useful, clean, cost-effective method of RSM to acquire these biologically active compounds from E. bulbosa bulb that could be utilised in food applications and future pharmaceutical industries.
format Article
author Kamarudin, Ammar Akram
Mohd. Esa, Norhaizan
Saad, Norazalina
Sayuti, Nor Hafiza
Ab. Razak, Nor asma
spellingShingle Kamarudin, Ammar Akram
Mohd. Esa, Norhaizan
Saad, Norazalina
Sayuti, Nor Hafiza
Ab. Razak, Nor asma
Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology
author_facet Kamarudin, Ammar Akram
Mohd. Esa, Norhaizan
Saad, Norazalina
Sayuti, Nor Hafiza
Ab. Razak, Nor asma
author_sort Kamarudin, Ammar Akram
title Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology
title_short Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology
title_full Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology
title_fullStr Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology
title_full_unstemmed Heat assisted extraction of phenolic compounds from Eleutherine bulbosa (Mill.) bulb and its bioactive profiles using response surface methodology
title_sort heat assisted extraction of phenolic compounds from eleutherine bulbosa (mill.) bulb and its bioactive profiles using response surface methodology
publisher Elsevier
publishDate 2020
url http://psasir.upm.edu.my/id/eprint/89163/1/BULB.pdf
http://psasir.upm.edu.my/id/eprint/89163/
https://www.sciencedirect.com/science/article/pii/S092666901931074X
_version_ 1712286754455683072
score 13.211869

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