REST and neural gene network Dysregulation in iPSC models of Alzheimer’s disease
The molecular basis of the earliest neuronal changes that lead to Alzheimer’s disease (AD) is unclear. Here, we analyze neural cells derived from sporadic AD (SAD), APOE4 gene-edited and control induced pluripotent stem cells (iPSCs). We observe major differences in iPSC-derived neural progenitor (N...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cell Press
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/82010/1/REST%20and%20neural%20gene%20network%20.pdf http://psasir.upm.edu.my/id/eprint/82010/ https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30032-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124719300324%3Fshowall%3Dtrue |
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