Cover Image

Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids

Flavonoids are polyphenols that are important organic chemicals in plants. The health benefits of flavonoids that result in high commercial values make them attractive targets for large-scale production through bioengineering. Strategies such as engineering a flavonoid biosynthetic pathway in microb...

Full description

Saved in:
Bibliographic Details
Main Authors: Azman Shah, Fatin Lyana, Ramzi, Ahmad Bazli, Baharum, Syarul, Mohd Noor, Normah, Goh, Hoe Han, Leow, Thean Chor, Oslan, Siti Nurbaya, Sabri, Suriana
Format: Article
Language:English
Published: Springer 2019
Online Access:http://psasir.upm.edu.my/id/eprint/81938/1/Recent%20advancement%20of%20engineering%20microbial.pdf
http://psasir.upm.edu.my/id/eprint/81938/
https://link.springer.com/article/10.1007%2Fs11033-019-05066-1
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.upm.eprints.81938
record_format eprints
spelling my.upm.eprints.819382021-09-29T01:52:15Z http://psasir.upm.edu.my/id/eprint/81938/ Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids Azman Shah, Fatin Lyana Ramzi, Ahmad Bazli Baharum, Syarul Mohd Noor, Normah Goh, Hoe Han Leow, Thean Chor Oslan, Siti Nurbaya Sabri, Suriana Flavonoids are polyphenols that are important organic chemicals in plants. The health benefits of flavonoids that result in high commercial values make them attractive targets for large-scale production through bioengineering. Strategies such as engineering a flavonoid biosynthetic pathway in microbial hosts provide an alternative way to produce these beneficial compounds. Escherichia coli, Saccharomyces cerevisiae and Streptomyces sp. are among the expression systems used to produce recombinant products, as well as for the production of flavonoid compounds through various bioengineering approaches including clustered regularly interspaced short palindromic repeats (CRISPR)-based genome engineering and genetically encoded biosensors to detect flavonoid biosynthesis. In this study, we review the recent advances in engineering model microbial hosts as being the factory to produce targeted flavonoid compounds. Springer 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81938/1/Recent%20advancement%20of%20engineering%20microbial.pdf Azman Shah, Fatin Lyana and Ramzi, Ahmad Bazli and Baharum, Syarul and Mohd Noor, Normah and Goh, Hoe Han and Leow, Thean Chor and Oslan, Siti Nurbaya and Sabri, Suriana (2019) Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids. Molecular Biology Reports, 46 (11). pp. 6647-6659. ISSN 0301-4851; ESSN: 1573-4978 https://link.springer.com/article/10.1007%2Fs11033-019-05066-1 10.1007/s11033-019-05066-1
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Flavonoids are polyphenols that are important organic chemicals in plants. The health benefits of flavonoids that result in high commercial values make them attractive targets for large-scale production through bioengineering. Strategies such as engineering a flavonoid biosynthetic pathway in microbial hosts provide an alternative way to produce these beneficial compounds. Escherichia coli, Saccharomyces cerevisiae and Streptomyces sp. are among the expression systems used to produce recombinant products, as well as for the production of flavonoid compounds through various bioengineering approaches including clustered regularly interspaced short palindromic repeats (CRISPR)-based genome engineering and genetically encoded biosensors to detect flavonoid biosynthesis. In this study, we review the recent advances in engineering model microbial hosts as being the factory to produce targeted flavonoid compounds.
format Article
author Azman Shah, Fatin Lyana
Ramzi, Ahmad Bazli
Baharum, Syarul
Mohd Noor, Normah
Goh, Hoe Han
Leow, Thean Chor
Oslan, Siti Nurbaya
Sabri, Suriana
spellingShingle Azman Shah, Fatin Lyana
Ramzi, Ahmad Bazli
Baharum, Syarul
Mohd Noor, Normah
Goh, Hoe Han
Leow, Thean Chor
Oslan, Siti Nurbaya
Sabri, Suriana
Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids
author_facet Azman Shah, Fatin Lyana
Ramzi, Ahmad Bazli
Baharum, Syarul
Mohd Noor, Normah
Goh, Hoe Han
Leow, Thean Chor
Oslan, Siti Nurbaya
Sabri, Suriana
author_sort Azman Shah, Fatin Lyana
title Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids
title_short Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids
title_full Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids
title_fullStr Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids
title_full_unstemmed Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids
title_sort recent advancement of engineering microbial hosts for the biotechnological production of flavonoids
publisher Springer
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/81938/1/Recent%20advancement%20of%20engineering%20microbial.pdf
http://psasir.upm.edu.my/id/eprint/81938/
https://link.springer.com/article/10.1007%2Fs11033-019-05066-1
_version_ 1712286735093727232
score 13.211869

Similar Items