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Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections

A study was carried out to screen for phytochemical constituents and assess the antioxidant and antimicrobial activities of Senna alata and Senna tora leaf extracts. The leaves were first dried at room temperature and 50°C in an oven prior to solvent extraction using ethanol and methanol. The in-vit...

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Main Authors: Nordin, Nornasriq Akmal, Mohd Zin, Nur Bainun, Fazilah, Nurul Farhana, Wasoh, Helmi, Ariff, Arbakariya, Halim, Murni
Format: Article
Language:English
Published: SciCell s.r.o. 2019
Online Access:http://psasir.upm.edu.my/id/eprint/81741/1/Phytochemicals%2C%20antioxidant%20and%20antimicrobial.pdf
http://psasir.upm.edu.my/id/eprint/81741/
https://office.scicell.org/index.php/BE/issue/view/3
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spelling my.upm.eprints.817412022-12-14T07:47:15Z http://psasir.upm.edu.my/id/eprint/81741/ Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections Nordin, Nornasriq Akmal Mohd Zin, Nur Bainun Fazilah, Nurul Farhana Wasoh, Helmi Ariff, Arbakariya Halim, Murni A study was carried out to screen for phytochemical constituents and assess the antioxidant and antimicrobial activities of Senna alata and Senna tora leaf extracts. The leaves were first dried at room temperature and 50°C in an oven prior to solvent extraction using ethanol and methanol. The in-vitro qualitative assays showed that both S. alata and S. tora leaf extracts contained bioactive and secondary metabolites components such as tannins, steroids, saponin, terpenoids, glycosides, flavonoids and phenols. The antioxidant activity and capacity test were carried out by conducting free radical of 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and Ferric reduction antioxidant plasma (FRAP) assays. Both assays showed S. tora leaf extract has higher antioxidant capacity than S. alata leaf extract. The efficacy of these leaf extracts were tested against skin pathogens through agar well diffusion method. S. alata extract showed an inhibition zone (1.15 –1.59 mm) against Pseudomonas aeruginosa while S. tora extracts exhibited a strong antimicrobial activity against S. epidermidis (inhibition zone of 12 –16.94 mm) followed by P. aeruginosa (inhibition zone of 1 –1.59 mm). Nonetheless, no inhibition zone was observed for S. aureus by both leaf extracts. The phytochemicals and antioxidant constituents as well as inhibitory potential on skin pathogens possessed by S. alata and S. tora leave highlighted their potential utilization in the development of natural drugs or cosmetics to treat skin related diseases or infections. SciCell s.r.o. 2019-01-23 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81741/1/Phytochemicals%2C%20antioxidant%20and%20antimicrobial.pdf Nordin, Nornasriq Akmal and Mohd Zin, Nur Bainun and Fazilah, Nurul Farhana and Wasoh, Helmi and Ariff, Arbakariya and Halim, Murni (2019) Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections. Bacterial Empire, 2 (1). pp. 19-25. ISSN 2585-9374 https://office.scicell.org/index.php/BE/issue/view/3 10.36547/be.2019.2.1.19-25
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description A study was carried out to screen for phytochemical constituents and assess the antioxidant and antimicrobial activities of Senna alata and Senna tora leaf extracts. The leaves were first dried at room temperature and 50°C in an oven prior to solvent extraction using ethanol and methanol. The in-vitro qualitative assays showed that both S. alata and S. tora leaf extracts contained bioactive and secondary metabolites components such as tannins, steroids, saponin, terpenoids, glycosides, flavonoids and phenols. The antioxidant activity and capacity test were carried out by conducting free radical of 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and Ferric reduction antioxidant plasma (FRAP) assays. Both assays showed S. tora leaf extract has higher antioxidant capacity than S. alata leaf extract. The efficacy of these leaf extracts were tested against skin pathogens through agar well diffusion method. S. alata extract showed an inhibition zone (1.15 –1.59 mm) against Pseudomonas aeruginosa while S. tora extracts exhibited a strong antimicrobial activity against S. epidermidis (inhibition zone of 12 –16.94 mm) followed by P. aeruginosa (inhibition zone of 1 –1.59 mm). Nonetheless, no inhibition zone was observed for S. aureus by both leaf extracts. The phytochemicals and antioxidant constituents as well as inhibitory potential on skin pathogens possessed by S. alata and S. tora leave highlighted their potential utilization in the development of natural drugs or cosmetics to treat skin related diseases or infections.
format Article
author Nordin, Nornasriq Akmal
Mohd Zin, Nur Bainun
Fazilah, Nurul Farhana
Wasoh, Helmi
Ariff, Arbakariya
Halim, Murni
spellingShingle Nordin, Nornasriq Akmal
Mohd Zin, Nur Bainun
Fazilah, Nurul Farhana
Wasoh, Helmi
Ariff, Arbakariya
Halim, Murni
Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections
author_facet Nordin, Nornasriq Akmal
Mohd Zin, Nur Bainun
Fazilah, Nurul Farhana
Wasoh, Helmi
Ariff, Arbakariya
Halim, Murni
author_sort Nordin, Nornasriq Akmal
title Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections
title_short Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections
title_full Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections
title_fullStr Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections
title_full_unstemmed Phytochemicals, antioxidant and antimicrobial properties of Senna alata and Senna tora leaf extracts against bacterial strains causing skin infections
title_sort phytochemicals, antioxidant and antimicrobial properties of senna alata and senna tora leaf extracts against bacterial strains causing skin infections
publisher SciCell s.r.o.
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/81741/1/Phytochemicals%2C%20antioxidant%20and%20antimicrobial.pdf
http://psasir.upm.edu.my/id/eprint/81741/
https://office.scicell.org/index.php/BE/issue/view/3
_version_ 1753789919705169920
score 13.211869

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