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Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application

Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and po...

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Main Authors: Misni, Norashiqin, Mohamed Nor, Zurainee, Ahmad, Rohani
Format: Article
Language:English
Published: Iranian Journal of Pharmaceutical Research 2019
Online Access:http://psasir.upm.edu.my/id/eprint/81354/1/Microencapsulation%20of%20Citrus%20grandis%20peel%20oil%20using%20interfacial%20precipitation%20chemistry%20technique%20for%20repellent%20application.pdf
http://psasir.upm.edu.my/id/eprint/81354/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487429/
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spelling my.upm.eprints.813542021-02-22T20:05:15Z http://psasir.upm.edu.my/id/eprint/81354/ Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application Misni, Norashiqin Mohamed Nor, Zurainee Ahmad, Rohani Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and potency of the repellent. In this study, Citrus grandis peel oil (CGPO) was encapsulated by using the interfacial precipitation chemistry technique. The microencapsulated CGPO was then formulated into lotion form to produce topical repellent formulation. This study includes the characterization of microcapsules with regards to the morphology, size distribution, zeta potential, Fourier Transmission Infrared spectrophotometer (FTIR), and Thermogravity analysis (TGA). The effectiveness of the microencapsulated CGPO-lotion formulation against mosquitoes was evaluated in the laboratory setting. Results indicated that CGPO have been successfully encapsulated with 6.5 µm in diameter and zeta potential values, -47.9 mV. The FTIR analysis spectrum indicated the presence of interaction between the wall materials in microcapsules. The TGA analysis demonstrated that microencapsulation improved the thermal stability of CGPO. Repellency assay revealed that microencapsulated CGPO- based formulation possessed excellent effect compared with pure CGPO. In conclusion, CGPO was successfully encapsulated and the microencapsulation aid to improve the repellency effect of CGPO against mosquito bites. Iranian Journal of Pharmaceutical Research 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81354/1/Microencapsulation%20of%20Citrus%20grandis%20peel%20oil%20using%20interfacial%20precipitation%20chemistry%20technique%20for%20repellent%20application.pdf Misni, Norashiqin and Mohamed Nor, Zurainee and Ahmad, Rohani (2019) Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application. Iranian Journal of Pharmaceutical Research, 18 (1). pp. 198-209. ISSN 1735-0328; ESSN: 1726-6890 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487429/
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and potency of the repellent. In this study, Citrus grandis peel oil (CGPO) was encapsulated by using the interfacial precipitation chemistry technique. The microencapsulated CGPO was then formulated into lotion form to produce topical repellent formulation. This study includes the characterization of microcapsules with regards to the morphology, size distribution, zeta potential, Fourier Transmission Infrared spectrophotometer (FTIR), and Thermogravity analysis (TGA). The effectiveness of the microencapsulated CGPO-lotion formulation against mosquitoes was evaluated in the laboratory setting. Results indicated that CGPO have been successfully encapsulated with 6.5 µm in diameter and zeta potential values, -47.9 mV. The FTIR analysis spectrum indicated the presence of interaction between the wall materials in microcapsules. The TGA analysis demonstrated that microencapsulation improved the thermal stability of CGPO. Repellency assay revealed that microencapsulated CGPO- based formulation possessed excellent effect compared with pure CGPO. In conclusion, CGPO was successfully encapsulated and the microencapsulation aid to improve the repellency effect of CGPO against mosquito bites.
format Article
author Misni, Norashiqin
Mohamed Nor, Zurainee
Ahmad, Rohani
spellingShingle Misni, Norashiqin
Mohamed Nor, Zurainee
Ahmad, Rohani
Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
author_facet Misni, Norashiqin
Mohamed Nor, Zurainee
Ahmad, Rohani
author_sort Misni, Norashiqin
title Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_short Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_full Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_fullStr Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_full_unstemmed Microencapsulation of Citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
title_sort microencapsulation of citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application
publisher Iranian Journal of Pharmaceutical Research
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/81354/1/Microencapsulation%20of%20Citrus%20grandis%20peel%20oil%20using%20interfacial%20precipitation%20chemistry%20technique%20for%20repellent%20application.pdf
http://psasir.upm.edu.my/id/eprint/81354/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487429/
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score 13.211869

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