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Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity

The objective of this study was to compare the antioxidant activity and cytotoxicity of Durio zibethinus M. (Durian) leaf extract from two extraction methods. Ultrasound-assisted extraction and Accelerated-solvent extraction were used to produce crude extract. The results revealed that UAE achieved...

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Main Authors: Yee, Joanne Kam Wai, Abas, Faridah, Hussain, Norhayati, Mirhosseini, Hamed
Format: Article
Language:English
Published: Taylor & Francis 2019
Online Access:http://psasir.upm.edu.my/id/eprint/80981/1/DURIO.pdf
http://psasir.upm.edu.my/id/eprint/80981/
https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1564296?journalCode=gnpl20
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spelling my.upm.eprints.809812020-10-14T20:54:12Z http://psasir.upm.edu.my/id/eprint/80981/ Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity Yee, Joanne Kam Wai Abas, Faridah Hussain, Norhayati Mirhosseini, Hamed The objective of this study was to compare the antioxidant activity and cytotoxicity of Durio zibethinus M. (Durian) leaf extract from two extraction methods. Ultrasound-assisted extraction and Accelerated-solvent extraction were used to produce crude extract. The results revealed that UAE achieved 3× higher in total phenolic content in the leaf extract compared to ASE. DPPH radical scavenging activity was 4.6× higher in leaf extract from ASE. No significant differences reported in ferric reducing power, and total flavonoid content of the leaf extract between the two methods. Cytotoxicity via MTT assay demonstrated no significant differences in cell viability upon exposure to the leaf extract from both methods. This suggested that they were appropriate in producing Durio zibethinus M. leaf extract for end use application in food related product. Both ensured similar level of safety in Durio zibethinus M. leaf extract as a new potential ingredient for the food industry. Taylor & Francis 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/80981/1/DURIO.pdf Yee, Joanne Kam Wai and Abas, Faridah and Hussain, Norhayati and Mirhosseini, Hamed (2019) Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity. Natural Product Research, 34 (13). pp. 1937-1941. ISSN 1478-6419; ESSN: 1478-6427 https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1564296?journalCode=gnpl20 10.1080/14786419.2018.1564296
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description The objective of this study was to compare the antioxidant activity and cytotoxicity of Durio zibethinus M. (Durian) leaf extract from two extraction methods. Ultrasound-assisted extraction and Accelerated-solvent extraction were used to produce crude extract. The results revealed that UAE achieved 3× higher in total phenolic content in the leaf extract compared to ASE. DPPH radical scavenging activity was 4.6× higher in leaf extract from ASE. No significant differences reported in ferric reducing power, and total flavonoid content of the leaf extract between the two methods. Cytotoxicity via MTT assay demonstrated no significant differences in cell viability upon exposure to the leaf extract from both methods. This suggested that they were appropriate in producing Durio zibethinus M. leaf extract for end use application in food related product. Both ensured similar level of safety in Durio zibethinus M. leaf extract as a new potential ingredient for the food industry.
format Article
author Yee, Joanne Kam Wai
Abas, Faridah
Hussain, Norhayati
Mirhosseini, Hamed
spellingShingle Yee, Joanne Kam Wai
Abas, Faridah
Hussain, Norhayati
Mirhosseini, Hamed
Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
author_facet Yee, Joanne Kam Wai
Abas, Faridah
Hussain, Norhayati
Mirhosseini, Hamed
author_sort Yee, Joanne Kam Wai
title Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
title_short Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
title_full Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
title_fullStr Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
title_full_unstemmed Comparison of crude extract from durio zibethinus M. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
title_sort comparison of crude extract from durio zibethinus m. (durian) leaf waste via ultrasound-assisted extraction and accelerated solvent extraction: antioxidant activity and cytotoxicity
publisher Taylor & Francis
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/80981/1/DURIO.pdf
http://psasir.upm.edu.my/id/eprint/80981/
https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1564296?journalCode=gnpl20
_version_ 1681490837628780544
score 13.211869

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