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Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most comm...

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Main Authors: Al-Battawi, Samer, Ho, Yu Bin, Latif, Mohd Talib, How, Vivien, Karuppiah, Thilakavathy
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019
Online Access:http://psasir.upm.edu.my/id/eprint/76448/1/2019121207430924_MJMHS_0326.pdf
http://psasir.upm.edu.my/id/eprint/76448/
https://medic.upm.edu.my/upload/dokumen/2019121207430924_MJMHS_0326.pdf
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spelling my.upm.eprints.764482020-02-04T04:53:59Z http://psasir.upm.edu.my/id/eprint/76448/ Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review Al-Battawi, Samer Ho, Yu Bin Latif, Mohd Talib How, Vivien Karuppiah, Thilakavathy Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most common techniques for extraction and clean-up procedures as it needs low quantity of solvents with less manual efforts. Similarly, various analytical instruments like gas chromatography coupled to mass spectrometry (GC-MS) was used to measure the PAHs levels. Gas chromatography is a simple, fast, and very efficient method for solvents and small organic molecules. This review provides an overview of the measured concentrations of PAHs in human blood samples through the application of SPE and GC-MS during the last ten years. While these studies used various solvents, their application of SPE method and GC-MS revealed rewarding results about the determination of PAHs levels in the human samples. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/76448/1/2019121207430924_MJMHS_0326.pdf Al-Battawi, Samer and Ho, Yu Bin and Latif, Mohd Talib and How, Vivien and Karuppiah, Thilakavathy (2019) Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review. Malaysian Journal of Medicine and Health Sciences, 15 (SP4). pp. 165-169. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019121207430924_MJMHS_0326.pdf
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most common techniques for extraction and clean-up procedures as it needs low quantity of solvents with less manual efforts. Similarly, various analytical instruments like gas chromatography coupled to mass spectrometry (GC-MS) was used to measure the PAHs levels. Gas chromatography is a simple, fast, and very efficient method for solvents and small organic molecules. This review provides an overview of the measured concentrations of PAHs in human blood samples through the application of SPE and GC-MS during the last ten years. While these studies used various solvents, their application of SPE method and GC-MS revealed rewarding results about the determination of PAHs levels in the human samples.
format Article
author Al-Battawi, Samer
Ho, Yu Bin
Latif, Mohd Talib
How, Vivien
Karuppiah, Thilakavathy
spellingShingle Al-Battawi, Samer
Ho, Yu Bin
Latif, Mohd Talib
How, Vivien
Karuppiah, Thilakavathy
Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
author_facet Al-Battawi, Samer
Ho, Yu Bin
Latif, Mohd Talib
How, Vivien
Karuppiah, Thilakavathy
author_sort Al-Battawi, Samer
title Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
title_short Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
title_full Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
title_fullStr Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
title_full_unstemmed Determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
title_sort determination of polycyclic aromatic hydrocarbons in human blood samples using solid phase extraction and gas chromatography mass spectrometry- a review
publisher Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
publishDate 2019
url http://psasir.upm.edu.my/id/eprint/76448/1/2019121207430924_MJMHS_0326.pdf
http://psasir.upm.edu.my/id/eprint/76448/
https://medic.upm.edu.my/upload/dokumen/2019121207430924_MJMHS_0326.pdf
_version_ 1662756524671369216
score 13.211869

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