Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein
In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins. Studies involving XRD, EDX, UV–Vis-NIR, and AFM analyses proved the presence of CdSQDs and PAMAM na...
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2018
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my.upm.eprints.751472020-04-20T15:41:18Z http://psasir.upm.edu.my/id/eprint/75147/ Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein Sheh Omar, Nur Alia Yap, Wing Fen Abdullah, Jaafar Anas, Nur Ain Asyiqin Md Ramdzan, Nur Syahira Mahdi, Mohd Adzir In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins. Studies involving XRD, EDX, UV–Vis-NIR, and AFM analyses proved the presence of CdSQDs and PAMAM nanoparticles. The mechanism of sensor surface functionalization was confirmed using FTIR spectra. The SPR responses showed a significant shift in resonance angle after exposure to different concentrations of DENV E-protein solution. From this observation, the Au/CdSQDs-PAMAM/IgM sensor film obtained a quantification limit of 0.0001 nM with the association constant of 2.53 × 103 M−1, which was better compared to the Au/IgM and Au/PAMAM/IgM sensor films. The matrix analysis was successfully performed using spiked bovine serum albumin obtaining excellent recovery values in the results. The enhancement of the SPR responses thus showing the high potential of CdSQDs-PAMAM thin film as dengue sensing material in SPR techniques for the future development of dengue diagnostic. Elsevier 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/75147/1/Optical%20and%20structural%20properties%20of%20cadmium%20sulphide%20quantum%20dots%20based%20thin%20%EF%AC%81lms%20as%20potential%20sensing%20material%20for%20dengue%20virus%20E-protein.pdf Sheh Omar, Nur Alia and Yap, Wing Fen and Abdullah, Jaafar and Anas, Nur Ain Asyiqin and Md Ramdzan, Nur Syahira and Mahdi, Mohd Adzir (2018) Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein. Results in Physics, 11. 734 - 739. ISSN 2211-3797 10.1016/j.rinp.2018.10.032 |
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In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins. Studies involving XRD, EDX, UV–Vis-NIR, and AFM analyses proved the presence of CdSQDs and PAMAM nanoparticles. The mechanism of sensor surface functionalization was confirmed using FTIR spectra. The SPR responses showed a significant shift in resonance angle after exposure to different concentrations of DENV E-protein solution. From this observation, the Au/CdSQDs-PAMAM/IgM sensor film obtained a quantification limit of 0.0001 nM with the association constant of 2.53 × 103 M−1, which was better compared to the Au/IgM and Au/PAMAM/IgM sensor films. The matrix analysis was successfully performed using spiked bovine serum albumin obtaining excellent recovery values in the results. The enhancement of the SPR responses thus showing the high potential of CdSQDs-PAMAM thin film as dengue sensing material in SPR techniques for the future development of dengue diagnostic. |
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Sheh Omar, Nur Alia Yap, Wing Fen Abdullah, Jaafar Anas, Nur Ain Asyiqin Md Ramdzan, Nur Syahira Mahdi, Mohd Adzir |
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Sheh Omar, Nur Alia Yap, Wing Fen Abdullah, Jaafar Anas, Nur Ain Asyiqin Md Ramdzan, Nur Syahira Mahdi, Mohd Adzir Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein |
author_facet |
Sheh Omar, Nur Alia Yap, Wing Fen Abdullah, Jaafar Anas, Nur Ain Asyiqin Md Ramdzan, Nur Syahira Mahdi, Mohd Adzir |
author_sort |
Sheh Omar, Nur Alia |
title |
Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein |
title_short |
Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein |
title_full |
Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein |
title_fullStr |
Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein |
title_full_unstemmed |
Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein |
title_sort |
optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus e-protein |
publisher |
Elsevier |
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2018 |
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http://psasir.upm.edu.my/id/eprint/75147/1/Optical%20and%20structural%20properties%20of%20cadmium%20sulphide%20quantum%20dots%20based%20thin%20%EF%AC%81lms%20as%20potential%20sensing%20material%20for%20dengue%20virus%20E-protein.pdf http://psasir.upm.edu.my/id/eprint/75147/ |
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13.211869 |