Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein

In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins. Studies involving XRD, EDX, UV–Vis-NIR, and AFM analyses proved the presence of CdSQDs and PAMAM na...

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Main Authors: Sheh Omar, Nur Alia, Yap, Wing Fen, Abdullah, Jaafar, Anas, Nur Ain Asyiqin, Md Ramdzan, Nur Syahira, Mahdi, Mohd Adzir
Format: Article
Language:English
Published: Elsevier 2018
Online Access:http://psasir.upm.edu.my/id/eprint/75147/1/Optical%20and%20structural%20properties%20of%20cadmium%20sulphide%20quantum%20dots%20based%20thin%20%EF%AC%81lms%20as%20potential%20sensing%20material%20for%20dengue%20virus%20E-protein.pdf
http://psasir.upm.edu.my/id/eprint/75147/
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spelling my.upm.eprints.751472020-04-20T15:41:18Z http://psasir.upm.edu.my/id/eprint/75147/ Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein Sheh Omar, Nur Alia Yap, Wing Fen Abdullah, Jaafar Anas, Nur Ain Asyiqin Md Ramdzan, Nur Syahira Mahdi, Mohd Adzir In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins. Studies involving XRD, EDX, UV–Vis-NIR, and AFM analyses proved the presence of CdSQDs and PAMAM nanoparticles. The mechanism of sensor surface functionalization was confirmed using FTIR spectra. The SPR responses showed a significant shift in resonance angle after exposure to different concentrations of DENV E-protein solution. From this observation, the Au/CdSQDs-PAMAM/IgM sensor film obtained a quantification limit of 0.0001 nM with the association constant of 2.53 × 103 M−1, which was better compared to the Au/IgM and Au/PAMAM/IgM sensor films. The matrix analysis was successfully performed using spiked bovine serum albumin obtaining excellent recovery values in the results. The enhancement of the SPR responses thus showing the high potential of CdSQDs-PAMAM thin film as dengue sensing material in SPR techniques for the future development of dengue diagnostic. Elsevier 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/75147/1/Optical%20and%20structural%20properties%20of%20cadmium%20sulphide%20quantum%20dots%20based%20thin%20%EF%AC%81lms%20as%20potential%20sensing%20material%20for%20dengue%20virus%20E-protein.pdf Sheh Omar, Nur Alia and Yap, Wing Fen and Abdullah, Jaafar and Anas, Nur Ain Asyiqin and Md Ramdzan, Nur Syahira and Mahdi, Mohd Adzir (2018) Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein. Results in Physics, 11. 734 - 739. ISSN 2211-3797 10.1016/j.rinp.2018.10.032
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
language English
description In this work, cadmium sulfide quantum dots composited with polyamidoamine dendrimer (CdSQDs-PAMAM) thin film had been successfully developed for use in the detection of dengue virus (DENV) E-proteins. Studies involving XRD, EDX, UV–Vis-NIR, and AFM analyses proved the presence of CdSQDs and PAMAM nanoparticles. The mechanism of sensor surface functionalization was confirmed using FTIR spectra. The SPR responses showed a significant shift in resonance angle after exposure to different concentrations of DENV E-protein solution. From this observation, the Au/CdSQDs-PAMAM/IgM sensor film obtained a quantification limit of 0.0001 nM with the association constant of 2.53 × 103 M−1, which was better compared to the Au/IgM and Au/PAMAM/IgM sensor films. The matrix analysis was successfully performed using spiked bovine serum albumin obtaining excellent recovery values in the results. The enhancement of the SPR responses thus showing the high potential of CdSQDs-PAMAM thin film as dengue sensing material in SPR techniques for the future development of dengue diagnostic.
format Article
author Sheh Omar, Nur Alia
Yap, Wing Fen
Abdullah, Jaafar
Anas, Nur Ain Asyiqin
Md Ramdzan, Nur Syahira
Mahdi, Mohd Adzir
spellingShingle Sheh Omar, Nur Alia
Yap, Wing Fen
Abdullah, Jaafar
Anas, Nur Ain Asyiqin
Md Ramdzan, Nur Syahira
Mahdi, Mohd Adzir
Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein
author_facet Sheh Omar, Nur Alia
Yap, Wing Fen
Abdullah, Jaafar
Anas, Nur Ain Asyiqin
Md Ramdzan, Nur Syahira
Mahdi, Mohd Adzir
author_sort Sheh Omar, Nur Alia
title Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein
title_short Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein
title_full Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein
title_fullStr Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein
title_full_unstemmed Optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus E-protein
title_sort optical and structural properties of cadmium sulphide quantum dots based thin films as potential sensing material for dengue virus e-protein
publisher Elsevier
publishDate 2018
url http://psasir.upm.edu.my/id/eprint/75147/1/Optical%20and%20structural%20properties%20of%20cadmium%20sulphide%20quantum%20dots%20based%20thin%20%EF%AC%81lms%20as%20potential%20sensing%20material%20for%20dengue%20virus%20E-protein.pdf
http://psasir.upm.edu.my/id/eprint/75147/
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